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Artikel-Nr: (BOSSBS-3498R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3498R-CY5
Beschreibung: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
UOM: 1 * 100 µl


Lieferant: TriLink BioTechnologies
Beschreibung: 2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddGTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

New Product

Lieferant: TriLink BioTechnologies
Beschreibung: 2',3'-Dideoxythymidine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddTTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

New Product

Artikel-Nr: (ENZOBMLP2770100)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : BMLP2770100
Beschreibung: Highly-quenched, ultra-bright fluorogenic substrate for most MMPs. 6'-TAMRA fluorescence is thoroughly quenched by the TQ3 group until cleavage by MMPs separates the two moieties. The OMNIMMP® RED substrate offers key advantages over other MMP substrates.
UOM: 1 * 100 µG


Artikel-Nr: (BOSSBS-7546R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7546R-CY5.5
Beschreibung: This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].
UOM: 1 * 100 µl


Artikel-Nr: (90019.)
Lieferant: Biotium
Hersteller Artikel Nummer : 90019
Beschreibung: 6-TRITC (Tetramethylrhodamine 6-isothiocyanate chloride) is spectrally similar to TAMRA (90022). The isothiocyanate reactive group reacts with primary or secondary amines to form a thiourea bond linkage.
UOM: 1 * 5 mg


Lieferant: Avantor
Beschreibung: Allsep anion is a methacrylate based phase with quaternary ammonium functional groups, optimised for use with both suppressed and non-suppressed conductivity detection. They are recommended for applications involving inorganic anions, weak and strong acid ions, metal complexes and organic acids.

Lieferant: TriLink BioTechnologies
Beschreibung: 2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddATP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

New Product

Artikel-Nr: (201987-100G)
Lieferant: SIGMA ALDRICH MICROSCOPY
Hersteller Artikel Nummer : 201987-100G
Beschreibung: Acid yellow-17 (C.I. 18965), also known as Disodium 2, 5-dichloro-4-(5-hydroxy-3-methyl-4-(sulphophenylazo)pyrazol-1-yl) benzenesulphonate, and Yellow 2G is an anionic, reactive textile dye. This synthetic azo dye possesses a stable aromatic structure with SO₃H and OH groups. The applications of Acid yellow-17 are seen in detergent, soap, textile, printing, and cosmetic industries.
UOM: 1 * 100 g


Artikel-Nr: (ROCKMB-101-0500)
Lieferant: Rockland Immunochemicals
Hersteller Artikel Nummer : MB-101-0500
Beschreibung: Deoxyribonuclease I (usually called DNase I), is an endonuclease coded by the human gene DNASE1. DNase I is a nuclease that cleaves DNA preferentially at phosphodiester linkages adjacent to a pyrimidine nucleotide, yielding 5'-phosphate-terminated polynucleotides with a free hydroxyl group on position 3', on average producing tetranucleotides. It acts on single-stranded DNA, double-stranded DNA, and chromatin.
UOM: 1 * 0,5 KU


Lieferant: TriLink BioTechnologies
Beschreibung: 2',3'-Dideoxycytidine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddCTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

New Product

Artikel-Nr: (BOSSBS-13140R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13140R-A350
Beschreibung: Fanconi anemia (FA) is an autosomal recessive disorder characterized by bone marrow failure, birth defects and chromsomal instability (1,2). The FA Group C complementation group gene encodes the protein FANCC, which is located in both cytoplasmic and nuclear compartments. FANCC is expressed in a cell cycle-dependent manner, with the lowest levels at the G1/S boundary and the highest levels in the M-phase. The FANCC protein interacts with other FA complementation group proteins as well as non-FA proteins (3). A human a spectrin II (designated aSpIIs) acts as a scaffold to enhance interactions between FANCC and FANCA to form a nuclear complex (4,5). Another binding partner of FANCC is the BTB/POZ domain containing protein FAZF, which is a transcriptional repressor (6). In hematopoietic cells expressing mutant FANCC, PKR is constitutively phosphorylated and has increased binding affinity for double-stranded RNA (7,8), which suggests that FANCC indirectly suppresses the activity of PKR. These cells are also apoptotic and are hypersensitive to IFNg and TNFa (8). In addition, FANCC protein is involved in the activation of STAT1 through receptors for at least three hematopoietic growth and survival factors (8).
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-12032R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12032R-CY5
Beschreibung: Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.
UOM: 1 * 100 µl


Lieferant: Biotium
Beschreibung: CF® dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 40,000 MW, and contains a formaldehyde-fixable free-amine group.

Artikel-Nr: (BOSSBS-0013R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0013R-A350
Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0013R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0013R-CY5.5
Beschreibung: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
UOM: 1 * 100 µl


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