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Artikel-Nr: (IMMRIR1335)
Lieferant: ImmunoReagents
Hersteller Artikel Nummer : IR1335
Beschreibung: TRITC (Tetramethylrhodamine isothiocyanate) is a popular rhodamine derivative pink in Colour but emits a red-orange Colour upon Emission at 580 nm. TRITC is frequently paired with FITC in double labeling experiments and conjugated antibodies are often used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. These conjugates are best excited with the 532 nm spectral line of the He-Ne laser and are also recommended as a second Colour detection reagent in in situ hybridization applications. (Excitation/Emission = 555 nm/580 nm Emission Colour = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, DyLight 550).
UOM: 1 * 2 mg


Artikel-Nr: (IMMRIR1080)
Lieferant: ImmunoReagents
Hersteller Artikel Nummer : IR1080
Beschreibung: TRITC (Tetramethylrhodamine isothiocyanate) is a popular rhodamine derivative pink in color but emits a red-orange color upon Emission at 580 nm. TRITC is frequently paired with FITC in double labeling experiments and conjugated antibodies are often used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. These conjugates are best excited with the 532 nm spectral line of the He-Ne laser and are also recommended as a second color detection reagent in <i>in situ</i> hybridisation applications. (Excitation/Emission = 555 nm / 580 nm Emission Color = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, DyLight 550)
UOM: 1 * 0,5 mg


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Artikel-Nr: (BOSSBS-8730R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8730R
Beschreibung: FOXC2 is a member of forkhead/winged helix transcription factor family, whose members serve as key regulators in embryogenesis and cell differentiation (3). FOXC2 functions as a key regulator of adipocyte metabolism by increasing the sensitivity of the beta-adrenergic-cAMP-protein kinase A (PKA) signaling pathway through alteration of adipocyte PKA holoenzyme composition (4). Increased FOXC2 levels, induced by high fat diet, seem to counteract most of the symptoms associated with obesity (4). FOXC2 expression is also associated with the early stage of chondrogenic differentiation both in vivo and in vitro (3). FOXC2 haploinsufficiency results in Lymphedema-distichiasis (LD), an autosomal dominant disorder that classically presents as lymphedema of the limbs, and double rows of eyelashes (distichiasis) (5). Mutant mice null for FOXC2 show defects in axial and cranial skeletogenesis, suggesting a requirement of FOXC2 for skeletal tissue development (3). FOXC2 interacts with FOXC1 in the Notch signaling pathway (1) and in kidney and heart development (2).
UOM: 1 * 100 µl


Artikel-Nr: (9237-03)
Lieferant: Avantor
Beschreibung: For high performance liquid chromatography. UV cutoff 220 nm. Packaged under nitrogen.
UOM: 1 * 4 L


Lieferant: Merck
Beschreibung: Ascentis® Express AQ-C18 sind Hochgeschwindigkeits-Hochleistungs-Flüssigkeitschromatographiesäulen, die auf dem Fused-Core®-Partikeldesign basieren.

Lieferant: Merck
Beschreibung: Die schnellen und leistungsstarken Ascentis® Express-Flüssigkeitschromatographiesäulen basieren auf dem 160 Å Fused-Core®-Partikeldesign mit breiteren Poren, um ausreichend Platz für die langkettigen C30-Liganden zu bieten.

Lieferant: Thermo Fisher Scientific
Beschreibung: Optimise the performance of Agilent™ GC systems with these specifically designed injection port liners for Agilent instruments.

Artikel-Nr: (PPSA2140020)
Lieferant: PFENNIG REINIGUNGSTECHNIK
Hersteller Artikel Nummer : 2140020
Beschreibung: Mops with high area performance.
UOM:


Lieferant: VWR Chemicals
Beschreibung: Fast HiFi DNA Polymerase 2 U/µl is a proof reading DNA polymerase displaying the following features; high fidelity >60X Taq DNA Polymerase, ability to amplify problematic DNA targets, such as those with low to high GC content and ability to perform amplification on long DNA targets. lt is recommended for applications, which require extremely high fidelity such as cloning/subcloning, NGS applications and mutagenesis.

Lieferant: Merck
Beschreibung: With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in 'gradient grade' as well as 'isocratic grade'. This minimises the gradient effect of the solvent involved.
Lieferant: Merck
Beschreibung: BIOshell™ IgG 1000 Å Diphenyl ist eine Hochgeschwindigkeits-Hochleistungs-Flüssigkeitschromatographiesäule, die auf einem neuen (1000 Å) Fused-Core®-Partikeldesign mit weiten Poren basiert.

Artikel-Nr: (BOSSBS-5798R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5798R-A750
Beschreibung: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-5798R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5798R-A555
Beschreibung: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-2968R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2968R-HRP
Beschreibung: Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro. Human papillomaviruses (HPV) are small DNA viruses which infect epithelia of the skin and mucosa. Over 90 types have been identified and they mostly cause a variety of benign lesions such as warts and verrucae. However, some subtypes, notably types 16 and 18, 31 and 33, have been confirmed as agents which cause cervical cancer. The E6 protein is a transcriptional transactivator. Binds double-stranded DNA. This protein may be involved in the oncogenic potential of this virus (cervical neoplasia-associated virus).
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-2968R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2968R-FITC
Beschreibung: Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro. Human papillomaviruses (HPV) are small DNA viruses which infect epithelia of the skin and mucosa. Over 90 types have been identified and they mostly cause a variety of benign lesions such as warts and verrucae. However, some subtypes, notably types 16 and 18, 31 and 33, have been confirmed as agents which cause cervical cancer. The E6 protein is a transcriptional transactivator. Binds double-stranded DNA. This protein may be involved in the oncogenic potential of this virus (cervical neoplasia-associated virus).
UOM: 1 * 100 µl


Artikel-Nr: (521-4053)
Lieferant: Beckman Coulter
Hersteller Artikel Nummer : 368690
Beschreibung: JS-5.3 AllSpin swinging bucket (high performance) rotor and buckets. For use in Avanti J-E and J-26 XP Series centrifuges only. Includes tie-down knob.
UOM: 1 * 1 ST


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