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Anti-HLA-DRB1 Mouse Monoclonal Antibody (CF594) [clone: HLA-DRB/1067]

Lieferant: Biotium

Beschreibung: This MAb reacts with the beta-chain of HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. Its epitope is different from that of MAb L243. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Loss of HLA-DR expression is related to tumor microenvironment and predicts adverse outcome in diffuse large B-cell lymphoma.

Anti-HLA-DR Mouse Monoclonal Antibody (PerCP) [clone: L243]

Lieferant: Tonbo Biosciences

Beschreibung: The L243 antibody reacts with a member of the human MHC Class II antigens, HLA-DR. The HLA-DR antigen is expressed on B lymphocytes, activated T lymphocytes, activated NK cells, monocytes, macrophages, other antigen presenting cells and progenitor cells. The L243 antibody is specific to an epitope on the alpha subunit of the heterodimeric HLA-DR protein and binds a different epitope than the LN3 antibody clone. It does not cross-react with HLA-DP or HLA-DQ. This antibody is reported to be cross-reactive with non-human primates including Chimpanzee, Cynomolgus, Rhesus and Baboon. Please choose the appropriate format for each application.

Anti-HLA DR Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: MEM-267]

Artikel-Nr: (ABCAAB64676-100)

Lieferant: Abcam

Hersteller Artikel Nummer : AB64676-100

Beschreibung: Anti-HLA DR Mouse Monoclonal Antibody (PE (Phycoerythrin)) [clone: MEM-267]

UOM: 1 * 100 µG

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Anti-HLA DR Mouse Monoclonal Antibody (FITC (Fluorescein)) [clone: MEM-12]

Artikel-Nr: (ABCAAB28323-100)

Lieferant: Abcam

Hersteller Artikel Nummer : AB28323-100

Beschreibung: Anti-HLA DR Mouse Monoclonal Antibody (FITC (Fluorescein)) [clone: MEM-12]

UOM: 1 * 100 Tests

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Anti-MHC Class 2, DQ, DR, Polymorphic Mouse Monoclonal Antibody [clone: 10F104]

Artikel-Nr: (USBIM3887-43C)

Lieferant: US Biological

Hersteller Artikel Nummer : M3887-43C

Beschreibung: Anti-MHC Class 2, DQ, DR, Polymorphic Mouse Monoclonal Antibody [clone: 10F104]

UOM: 1 * 250 µG

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Anti-HLA-DRB1 Mouse Monoclonal Antibody (CF647) [clone: L243]

Lieferant: Biotium

Beschreibung: This MAb reacts with the HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. It binds a conformational epitope on HLA-DR, which depends on the correct folding of the α/β heterodimer. This MAb has been reported to block mixed lymphocyte reactions. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kD alpha (heavy) chain and a 28kD beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.