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Image Unavailable-BOSSBS-1698R-A750

Anti-ox-LDL Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-1698R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1698R-A750
Beschreibung: Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidised LDL is specifically recognised and ingested by macrophages via scavenger receptor A and CD36. oxidised LDL may be a marker of atherosclerosis but the precise changes in oxidised LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12501R-HRP

Anti-APOM Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-12501R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12501R-HRP
Beschreibung: Apolipoproteins are protein components of plasma lipoproteins. ApoM (Apolipoprotein M), also known as protein G3a, is a member of the Lipocalin family of proteins. ApoM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. Mature ApoM retains its signal peptide, which acts as a hydrophobic anchor, and contains a structurally conserved eight stranded antiparallel ∫ barrel which binds retinol and retinoic acid. ApoM may play a key role in reverse cholesterol transport. It mainly associates with high density lipoprotein (HDL) and to a lesser extent with triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). ApoM is important for the pre∫-HDL formation. Pre∫-HDL is an important acceptor of peripheral cellular cholesterol. The concentration of ApoM in plasma strongly correlates with total cholesterol. Low concentrations of ApoM in plasma is associated with diabetes.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-12501R-A647

Anti-APOM Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-12501R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12501R-A647
Beschreibung: Apolipoproteins are protein components of plasma lipoproteins. ApoM (Apolipoprotein M), also known as protein G3a, is a member of the Lipocalin family of proteins. ApoM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. Mature ApoM retains its signal peptide, which acts as a hydrophobic anchor, and contains a structurally conserved eight stranded antiparallel ∫ barrel which binds retinol and retinoic acid. ApoM may play a key role in reverse cholesterol transport. It mainly associates with high density lipoprotein (HDL) and to a lesser extent with triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). ApoM is important for the pre∫-HDL formation. Pre∫-HDL is an important acceptor of peripheral cellular cholesterol. The concentration of ApoM in plasma strongly correlates with total cholesterol. Low concentrations of ApoM in plasma is associated with diabetes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6480R-A680

Anti-CH25H Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-6480R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6480R-A680
Beschreibung: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesising a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5050R-A680

Anti-CYP39A1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-5050R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5050R-A680
Beschreibung: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5050R-A647

Anti-CYP39A1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-5050R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5050R-A647
Beschreibung: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2014R-A680

Anti-SCP2/NLTP Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-2014R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2014R-A680
Beschreibung: Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2200R-A750

Anti-LDL Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-2200R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2200R-A750
Beschreibung: LDL and HDL transport both dietary and endogenous cholesterol in the plasma. LDL is the main transporter of cholesterol and cholesteryl esters and makes up more than half of the total lipoprotein in plasma. LDL is absorbed by the liver and other tissues via receptor mediated endocytosis. The cytoplasmic domain of the LDL receptor facilitates the formation of coated pits; receptor-rich regions of the membrane. The ligand binding domain of the receptor Recognises apo-B100 on LDL, resulting in the formation of a clathrin-coated vesicle. ATP-dependent proton pumps lower the pH inside the vesicle resulting dissociation of LDL from its receptor. After loss of the clathrin coat the vesicles fuse with lysozomes, resulting in peptide and cholesteryl ester enzymatic hydrolysis. The LDL receptor can be recycled to the cell membrane. Insulin, tri-iodothyronine and dexamethasome have shown to be involved with the regulation of LDL receptor mediated uptake. The protein component of LDL is apolipoprotein B100. LDL contains 2022% protein, 1015% triglycerides, 2028% phospholipids, 3748% cholesteryl esters and 810% cholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2014R-HRP

Anti-SCP2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-2014R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2014R-HRP
Beschreibung: Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5013R-A680

Anti-ABCG5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-5013R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5013R-A680
Beschreibung: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4063R-A488

Anti-HMGCR Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-4063R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4063R-A488
Beschreibung: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5068R-A350

Anti-HMGCR Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-5068R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5068R-A350
Beschreibung: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4063R-CY3

Anti-HMGCR Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-4063R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4063R-CY3
Beschreibung: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4063R-HRP

Anti-HMGCR Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-4063R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4063R-HRP
Beschreibung: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15409R-HRP

Anti-CYP51A1 Rabbit Polyclonal Antibody (HRP)

Artikel-Nr: (BOSSBS-15409R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-15409R-HRP
Beschreibung: CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalysing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15409R-CY7

Anti-CYP51A1 Rabbit Polyclonal Antibody (Cy7)

Artikel-Nr: (BOSSBS-15409R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-15409R-CY7
Beschreibung: CYP51A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalysing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl
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