Beschreibung: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

Artikel-Nr: BOSSBS-7834R

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-7834R

Lieferant: Bioss

Sale

Beschreibung: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed:22422861, PubMed:24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPT1, VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity. Key regulator of active promoters in resting B- and T-lymphocytes.

Artikel-Nr: BOSSBS-2445R-CY7

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-2445R-CY7

Lieferant: Bioss

Sale

Beschreibung: C-Phycocyanin (CPC), a pigment-protein complex from the light-harvesting phycobiliprotein family.

Artikel-Nr: BOSSBS-0697R-A555

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-0697R-A555

Lieferant: Bioss

Sale

Beschreibung: C-Phycocyanin (CPC), a pigment-protein complex from the light-harvesting phycobiliprotein family.

Artikel-Nr: BOSSBS-0697R-A750

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-0697R-A750

Lieferant: Bioss

Sale

Beschreibung: Fittings connect in a snap.

Artikel-Nr: MFLX31313-13BLK

UOM: 1 * 10 ST

Hersteller Artikel Nummer : 31313-13BLK

Lieferant: Avantor Fluid Handling

Sale

Beschreibung: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

Artikel-Nr: BOSSBS-7834R-CY5

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-7834R-CY5

Lieferant: Bioss

Sale

Beschreibung: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

Artikel-Nr: BOSSBS-7834R-CY7

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-7834R-CY7

Lieferant: Bioss

Sale

Beschreibung: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

Artikel-Nr: BOSSBS-7834R-FITC

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-7834R-FITC

Lieferant: Bioss

Sale

Beschreibung: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed:22422861, PubMed:24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPT1, VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity. Key regulator of active promoters in resting B- and T-lymphocytes.

Artikel-Nr: BOSSBS-2445R-HRP

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-2445R-HRP

Lieferant: Bioss

Sale

Beschreibung: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed:22422861, PubMed:24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPT1, VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity. Key regulator of active promoters in resting B- and T-lymphocytes.

Artikel-Nr: BOSSBS-2445R-CY5.5

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-2445R-CY5.5

Lieferant: Bioss

Sale

Beschreibung: Schläuche knicken nicht mehr - ermöglicht das freie Rotieren der Schläuche.

Artikel-Nr: MFLX06363-52

UOM: 1 * 10 ST

Lieferant: Avantor Fluid Handling

Sale

Beschreibung: C-Phycocyanin (CPC), a pigment-protein complex from the light-harvesting phycobiliprotein family.

Artikel-Nr: BOSSBS-0697R-CY5

UOM: 1 * 100 µl

Hersteller Artikel Nummer : BS-0697R-CY5

Lieferant: Bioss

Sale

Beschreibung: Keine Leckagen - Kupplungen mit Ventil sperren automatisch den Durchfluss.

Artikel-Nr: MFLX31303-13BLK

UOM: 1 * 10 ST

Lieferant: Avantor Fluid Handling

Sale

Beschreibung: Fittings connect in a snap.

Artikel-Nr: MFLX31311-61BLK

UOM: 1 * 250 ST

Lieferant: Avantor Fluid Handling

Sale

Beschreibung: Keine Leckagen - Kupplungen mit Ventil sperren automatisch den Durchfluss.

Artikel-Nr: MFLX31307-46BLK

UOM: 1 * 10 ST

Lieferant: Avantor Fluid Handling

Sale

Beschreibung: Keine Leckagen - Kupplungen mit Ventil sperren automatisch den Durchfluss.

Artikel-Nr: MFLX31303-55BLK

UOM: 1 * 10 ST

Lieferant: Avantor Fluid Handling

Sale