Sie suchten nach: CPC+COLDER

Artikel-Nr: (BOSSBS-8048R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8048R-A488

Beschreibung: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-8048R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8048R-HRP

Beschreibung: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

UOM: 1 * 100 µl

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Lieferant: Avantor Fluid Handling

Beschreibung: Convenience of a quick-disconnect in pressure and vacuum applications.

Lieferant: Avantor Fluid Handling

Beschreibung: Keine Anstrengung mehr - einfach mit dem Daumen die Verriegelung öffnen.

Lieferant: Avantor Fluid Handling

Beschreibung: Save time - with one coupling you can connect two, six, or ten lines.

Artikel-Nr: (BOSSBS-7750R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-7750R-HRP

Beschreibung: Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-8048R-A750)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8048R-A750

Beschreibung: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localisation of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-8048R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8048R-CY5

Beschreibung: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-8048R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8048R-FITC

Beschreibung: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

UOM: 1 * 100 µl

Sale

Lieferant: Avantor Fluid Handling

Beschreibung: Keine Leckagen - Kupplungen mit Ventil sperren automatisch den Durchfluss.

Artikel-Nr: (BOSSBS-8048R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8048R-A680

Beschreibung: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localisation of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

UOM: 1 * 100 µl

Sale

Lieferant: Avantor Fluid Handling

Beschreibung: Schläuche knicken nicht mehr - ermöglicht das freie Rotieren der Schläuche.

Zertifikate

Artikel-Nr: (BOSSBS-2445R-A750)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2445R-A750

Beschreibung: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilisation and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage: phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed:22422861, PubMed:24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1, SEPT1, VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at 'Ser-10' and 'Ser-28' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively regulates its transcriptional activity. Key regulator of active promoters in resting B- and T-lymphocytes.

UOM: 1 * 100 µl

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Artikel-Nr: (ESCH1624521)

Lieferant: ESCHENBACH OPTIK

Hersteller Artikel Nummer : 1624521

Beschreibung: The MaxDetail® with LED headlight has a customized adapter, this allows the headlight to fit over the bridge of the telescope to provide hands-free illumination. The two bright LEDs provide an outstanding 3,200 lux of flicker-free illumination at 25 cm (approx. 10 inches from the object) or 1,200 lux at 40 cm (approx. 25,4 mm from the object). This high brightness is possible due, in part, to the incorporation of new CPC (Compound Parabolic Concentrator) optic technology.

UOM: 1 * 1 ST

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Artikel-Nr: (BOSSBS-8048R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8048R-CY3

Beschreibung: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-8048R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8048R-CY5.5

Beschreibung: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

UOM: 1 * 100 µl

Sale