Sie suchten nach: Bioss

Artikel-Nr: (BOSSBS-13555R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13555R-CY7

Beschreibung: ZBED5 contains 1 BED type zinc finger and it may be derived from an ancient transposon that has lost its ability to translocate. This gene is unusual in that its coding sequence is mostly derived from Charlie like DNA transposon. There is mRNA and EST evidence to suggest that this gene is transcribed. The encoded protein shares 70% identity with Charlie 1 transposase, however, this gene does not appear to be an active DNA transposon as it is not flanked by terminal inverted repeats. The exact function of this gene product is not known.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0912R-A555)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0912R-A555

Beschreibung: No data available.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6419R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6419R-A350

Beschreibung: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13555R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13555R-CY3

Beschreibung: ZBED5 contains 1 BED type zinc finger and it may be derived from an ancient transposon that has lost its ability to translocate. This gene is unusual in that its coding sequence is mostly derived from Charlie like DNA transposon. There is mRNA and EST evidence to suggest that this gene is transcribed. The encoded protein shares 70% identity with Charlie 1 transposase, however, this gene does not appear to be an active DNA transposon as it is not flanked by terminal inverted repeats. The exact function of this gene product is not known.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0912R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0912R-CY3

Beschreibung: No data available.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-2617R-A647)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2617R-A647

Beschreibung: Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine (By similarity).

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0912R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0912R-FITC

Beschreibung: No data available.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6243R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6243R-CY5.5

Beschreibung: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-2394R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2394R-A488

Beschreibung: May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10. Isoform 1 has chemotactic response in rat monocytes, neutrophils, and lymphocytes.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0787R-CY3)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0787R-CY3

Beschreibung: Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC â…  molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13345R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13345R-FITC

Beschreibung: The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46% sequence identity with GGA1 and 38% with GGA2.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0787R-A750)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0787R-A750

Beschreibung: Has antiviral, antibacterial and anticancer activities.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-2042R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-2042R-A680

Beschreibung: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13257R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13257R-CY5

Beschreibung: GAD-65 and GAD-67, glutamate decarboxylases function to catalyze the production of GABA (Gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0489R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0489R-A350

Beschreibung: The immunocytochemical detection of bromodeoxyuridine (BrdU) incorporated into DNA is a powerful tool to study the cytokinetics of normal and neoplastic cells. In vitro or in vivo labeling of tumor cells with the thymidine analogue BrdU and the subsequent detection of incorporated BrdU with specific anti-BrdU monoclonal is an accurate and comprehensive method to quantitate the degree of DNA-synthesis.BrdU is incorporated into the newly synthezised DNA of S-phase cells may provide an estimate for the fraction of cells in S-phase. Also dynamic proliferative information such as the S-phase transit rate and the potential doubling time can be obtained, by means of bivariate BrdU/DNA flow cytometric analysis

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-5859R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5859R-CY5.5

Beschreibung: ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration.A member of the metalloproteinase family containing disintegrin like domains (ADAMs), the function of ADAMTS8 is still poorly understood. ADAMTS8 contains the canonical HExxHxxxxxH zinc metalloproteinase motif, and has been shown to be proteolytically active on a range of substrates. ADAMTS8 is inhibited by the endogenous MMP inhibitors, TIMP1, 2, 3 and 4, but most efficiently by TIMP3. In addition to the metalloprotease domain, ADAMTS8 has a propeptide domain, a Prohormone Convertase (PC, furin) cleavage site, a cysteine rich domain and thrombospondin 1 like domains.

UOM: 1 * 100 µl

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