Sie suchten nach: Arabinofuranosyl-guanine+hydrate

Artikel-Nr: (BOSSBS-11582R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11582R-CY5

Beschreibung: Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation. Repac, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, with weaker expression in heart, placenta, lung, pancreas and small intestine. Existing as two alternatively spliced isoforms, the Repac gene is conserved in cow, mouse and rat. The gene that encodes Repac maps to human chromosome 7p15.3, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-13472R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13472R-HRP

Beschreibung: GTPases from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein Rpl25a to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like) is a 582 amino acid nuclear protein that belongs to the MMR1/HSR1 GTP-binding protein family. Containing one G (guanine nucleotide-binding) domain, GNL3L is required for normal processing of ribosomal pre-rRNA and for cell proliferation.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-13472R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13472R-A680

Beschreibung: GTPases from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein Rpl25a to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like) is a 582 amino acid nuclear protein that belongs to the MMR1/HSR1 GTP-binding protein family. Containing one G (guanine nucleotide-binding) domain, GNL3L is required for normal processing of ribosomal pre-rRNA and for cell proliferation.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-7768R-A555)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-7768R-A555

Beschreibung: Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1894R-A555)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1894R-A555

Beschreibung: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-13459R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13459R-A350

Beschreibung: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-3942R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-3942R-CY5

Beschreibung: GNB2 belongs to the WD repeat G protein beta family. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-4109R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4109R-A350

Beschreibung: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. May play a role in the control of cell migration through the TOR signaling cascade.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-0348R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0348R-CY5

Beschreibung: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-4109R-HRP)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4109R-HRP

Beschreibung: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. May play a role in the control of cell migration through the TOR signaling cascade.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-12866R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12866R-CY5

Beschreibung: Guanine nucleotide-exchange proteins (GEPs) accelerate replacement of bound GDP with GTP and thereby activate ADP-ribosylation factors (ARFs), a family of guanine nucleotide-binding proteins that play an important role in intracellular vesicular trafficking. GEPs comprise two major families, large GEPs that are inhibited by brefeldin A (BFA), a protein that effects Golgi structure and a group of smaller GEPs that are insenstive to BFA. Two genes for GEPs found on human chromosomes 8 and 20 encode BFA sensitive GEPs designated BIG1 and BIG2. Both GEPS contain a sec7 domain that is responsible for their brefeldin inhibition and also their catalytic activity. In vivo, BIG1 and BIG2 exist in macromolecular complexes that move between the Golgi membranes and cytosol. BIG2 associates with PKA regulatory subunits, implying that BIG2 may act as an A kinase-anchoring protein (AKAP) that could coordinate the cAMP and ARF regulatory pathways.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-13472R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13472R-FITC

Beschreibung: GTPases from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein Rpl25a to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like) is a 582 amino acid nuclear protein that belongs to the MMR1/HSR1 GTP-binding protein family. Containing one G (guanine nucleotide-binding) domain, GNL3L is required for normal processing of ribosomal pre-rRNA and for cell proliferation.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-0348R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-0348R-A350

Beschreibung: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-6962R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6962R-FITC

Beschreibung: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-3942R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-3942R-A488

Beschreibung: GNB2 belongs to the WD repeat G protein beta family. Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-10955R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10955R-A680

Beschreibung: Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).

UOM: 1 * 100 µl

Sale