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Image Unavailable-BOSSBS-3052R-A647

Anti-BCL2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-3052R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3052R-A647
Beschreibung: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15533R-A647

Anti-Bcl-2 Rabbit Polyclonal Antibody (ALEXA FLUOR® 647)

Artikel-Nr: (BOSSBS-15533R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-15533R-A647
Beschreibung: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-1696R-CY7

Anti-TNFRSF10B Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-1696R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1696R-CY7
Beschreibung: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5324R-CY5

Anti-FAS Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-5324R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5324R-CY5
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5323R-CY3

Anti-FAS Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-5323R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5323R-CY3
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4563R-HRP

Anti-BCL2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-4563R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4563R-HRP
Beschreibung: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15533R-A488

Anti-Bcl-2 Rabbit Polyclonal Antibody (ALEXA FLUOR® 488)

Artikel-Nr: (BOSSBS-15533R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-15533R-A488
Beschreibung: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3052R-A750

Anti-Bcl-2 Ser70 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-3052R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3052R-A750
Beschreibung: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0738R-CY3

Anti-BIRC7 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-0738R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-CY3
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0738R-CY5.5

Anti-BIRC7 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-0738R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-CY5.5
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5323R-A350

Anti-FAS Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-5323R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5323R-A350
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5324R-A488

Anti-FAS Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-5324R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5324R-A488
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5323R-HRP

Anti-FAS Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-5323R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5323R-HRP
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5323R

Anti-FAS Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-5323R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5323R
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6477R-HRP

Anti-FAS Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-6477R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6477R-HRP
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0081R-CY5

Anti-CASP3 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-0081R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0081R-CY5
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
UOM: 1 * 100 µl
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