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Image Unavailable-BOSSBS-0544R-HRP

Anti-CIDEB Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-0544R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0544R-HRP
Beschreibung: Activates apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5930R-A750

Anti-Centaurin gamma 1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-5930R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5930R-A750
Beschreibung: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-5324R-A680

Anti-CD95 Tyr232 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-5324R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5324R-A680
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5323R-A680

Anti-CD95 Tyr291 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-5323R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5323R-A680
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5323R-A750

Anti-CD95 Tyr291 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-5323R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5323R-A750
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-19301R-A750

Anti-nNOS Ser1417 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Artikel-Nr: (BOSSBS-19301R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-19301R-A750
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5241R-A680

Anti-Caspase-9 Ser196 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-5241R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5241R-A680
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0544R-CY5.5

Anti-CIDEB Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-0544R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0544R-CY5.5
Beschreibung: Activates apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0738R-CY3

Anti-BIRC7 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-0738R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-CY3
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0738R-CY5.5

Anti-BIRC7 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-0738R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-CY5.5
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3052R-A647

Anti-BCL2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-3052R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3052R-A647
Beschreibung: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15533R-A647

Anti-Bcl-2 Rabbit Polyclonal Antibody (ALEXA FLUOR® 647)

Artikel-Nr: (BOSSBS-15533R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-15533R-A647
Beschreibung: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1696R-CY5.5

Anti-TNFRSF10B Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-1696R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1696R-CY5.5
Beschreibung: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1696R-CY7

Anti-TNFRSF10B Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-1696R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1696R-CY7
Beschreibung: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3705R-A555

Anti-P53 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-3705R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3705R-A555
Beschreibung: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0033R-CY5.5

Anti-P53 Proteinwt-p53 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-0033R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0033R-CY5.5
Beschreibung: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
UOM: 1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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