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Anti-ITPR1 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-8869R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8869R-CY7
Beschreibung: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-19301R-A750

Anti-nNOS Ser1417 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Artikel-Nr: (BOSSBS-19301R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-19301R-A750
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl

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Anti-CENTG1 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-5930R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5930R-CY5
Beschreibung: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0544R-CY5.5

Anti-CIDEB Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-0544R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0544R-CY5.5
Beschreibung: Activates apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1696R-CY5.5

Anti-TNFRSF10B Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-1696R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1696R-CY5.5
Beschreibung: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1351R-CY7

Anti-GZMB Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-1351R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1351R-CY7
Beschreibung: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0738R-CY3

Anti-BIRC7 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-0738R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-CY3
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0738R-CY5.5

Anti-BIRC7 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-0738R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-CY5.5
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6477R-A555

Anti-FAS Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-6477R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6477R-A555
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6477R-A350

Anti-FAS Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-6477R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6477R-A350
Beschreibung: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1351R-A350

Anti-GZMB Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-1351R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1351R-A350
Beschreibung: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0050R-CY7

Anti-CASP9 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-0050R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0050R-CY7
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5241R-CY5.5

Anti-CASP9 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-5241R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5241R-CY5.5
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1696R-A350

Anti-TNFRSF10B Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-1696R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1696R-A350
Beschreibung: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1696R-FITC

Anti-TNFRSF10B Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-1696R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1696R-FITC
Beschreibung: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis (By similarity).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8502R-CY5.5

Anti-CASP9 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-8502R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8502R-CY5.5
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
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