Sie suchten nach: Apoptosis+activator+2


159'089  results were found

SearchResultCount:"159089"

Sort Results

Listenansicht Easy View

Bewerten Sie das Suchergebnis

Artikel-Nr: (BOSSBS-0738R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-A750
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-8869R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8869R-FITC
Beschreibung: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl


Neue Transparenz für europäische Kunden

Haben Sie an der Kasse unsere neue und verbesserte Sichtbarkeit des Lagerbestands bemerkt?

Weitere Informationen

Erweiterung der Lagerstandorte

Artikel-Nr: (BOSSBS-0738R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-FITC
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0738R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-A555
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-1870R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1870R-CY7
Beschreibung: Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-5241R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5241R-CY7
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-5241R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5241R-CY5
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0050R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0050R
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0050R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0050R-CY5
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0049R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0049R-CY3
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-1870R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1870R-A350
Beschreibung: Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-8869R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8869R-A750
Beschreibung: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-8869R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8869R-CY5
Beschreibung: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-0738R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-0738R-A647
Beschreibung: Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of CASP3, CASP7 and CASP9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits CASP3 and proteolytic activation of pro-CASP9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Isoform 2 protects against natural killer (NK) cell killing whereas isoform 1 augments killing.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-5241R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5241R-CY3
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-8502R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8502R-A488
Beschreibung: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
UOM: 1 * 100 µl


Inquire for Price
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Regulatory Affairs.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Das Produkt kann nicht in den Warenkorb gelegt werden.
Der Grund kann ein Preis auf Anfrage oder ein Artikelblock sein.
Bitte kontaktieren Sie Ihr zuständiges VWR Team für weitere Informationen
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Mit diesem Symbol gekennzeichnete Produkte werden nicht mehr angeboten - bis zum Ende des Lagerbestands verkauft. Alternativen können durch Suchen mit der oben aufgeführten VWR-Katalognummer verfügbar sein. Wenn Sie weitere Hilfe benötigen, rufen Sie bitte den VWR-Kundendienst an unter 044 745 13 13
17 - 32 of 159'089
no targeter for Bottom