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Artikel-Nr: (BOSSBS-9006R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9006R
Beschreibung: Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-9006R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9006R-A488
Beschreibung: Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.
UOM: 1 * 100 µl


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Artikel-Nr: (BOSSBS-9006R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9006R-A555
Beschreibung: Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-4235R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4235R-A555
Beschreibung: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-4235R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4235R-HRP
Beschreibung: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-4235R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4235R-A647
Beschreibung: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-4235R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4235R-A350
Beschreibung: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-5900R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5900R-HRP
Beschreibung: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
UOM: 1 * 100 µl


Artikel-Nr: (1012123.)
Lieferant: USP
Hersteller Artikel Nummer : 1012123
Beschreibung: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
UOM: 1 * 200 mg

Lieferant: ENZO LIFE SCIENCES
Beschreibung: Inhibits ERK2 (Ki = 525nM). Also inhibits adenosine kinase (Ki = 30nM), CK1 and CK2 and insulin receptor kinase (IC50 ranging from 0.4-28µM).

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Artikel-Nr: (BOSSBS-5900R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5900R-A750
Beschreibung: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-5900R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5900R-A680
Beschreibung: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-4235R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4235R-CY5
Beschreibung: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-4176R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4176R-CY7
Beschreibung: Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-4176R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4176R-A647
Beschreibung: Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
UOM: 1 * 100 µl


Artikel-Nr: (BOSSBS-4176R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-4176R-CY3
Beschreibung: Functions as a polyspecific organic cation transporter, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, dopamine, norepinephrine and epinephrine. May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters. May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption. Does not seem to transport nucleoside and nucleoside analogs such as uridine, cytidine, thymidine, adenosine, inosine, guanosine, and azidothymidine. In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, with maximal activity in the pH range 5.5 to 6.5. Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates. Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential. Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, dipyridamole, dilazep, and nitrobenzylthioinosine. May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, in particular during ischemia.
UOM: 1 * 100 µl


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