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Image Unavailable-BOSSBS-1163R-HRP

Anti-DEFB1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-1163R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1163R-HRP
Beschreibung: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11388R-CY5

Anti-AAMP Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-11388R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11388R-CY5
Beschreibung: AAMP is a 434 amino acid immunoglobulin-like protein that contains 8 WD repeats. Expressed in endothelial cells, cytotrophoblasts and blood vessels, AAMP is thought to have a heparin-sensitive role in cell adhesion and cell migration. AAMP is strongly expressed in poorly differentiated colon adenocarcinoma cells, suggesting a role for AAMP in tumor progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11388R-CY3

Anti-AAMP Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-11388R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11388R-CY3
Beschreibung: AAMP is a 434 amino acid immunoglobulin-like protein that contains 8 WD repeats. Expressed in endothelial cells, cytotrophoblasts and blood vessels, AAMP is thought to have a heparin-sensitive role in cell adhesion and cell migration. AAMP is strongly expressed in poorly differentiated colon adenocarcinoma cells, suggesting a role for AAMP in tumor progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11595R-A488

Anti-NOMO1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-11595R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11595R-A488
Beschreibung: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12485R-A680

Anti-APCL/APC2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-12485R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12485R-A680
Beschreibung: The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner's syndrome (GS), are characterised by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion. APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin. Interactions between cytoskeleton and the APC, E cadherin, b/g catenin complex are mediated by a-catenin.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12485R-A555

Anti-APC2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-12485R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12485R-A555
Beschreibung: The adenomatous polyposis syndromes, familial adenomatous polyposis (FAP) and Gardner’s syndrome (GS), are characterized by numerous adenomatous polyps throughout the entire colon. These polyps invariably progress to colon cancer in addition to other extracolonic manifestations. The cloning of the APC gene revealed a ubiquitously expressed protein, 2843 amino acids in length, which is frequently mutated in patients suffering from FAP and GS. APC has been found to be associated with structural components of intracellular junctions. b-catenin and g-catenin (also called plakoglobin) are involved in the regulation of cellular adhesion. APC and E cadherin compete for binding to specific internal regions of both b- and g-catenin. Interactions between cytoskeleton and the APC, E cadherin, b/g catenin complex are mediated by a-catenin.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8282R

Anti-DPH2 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-8282R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8282R
Beschreibung: DPH2 (diphthamide biosynthesis protein 2), also known as DPH2L2, is a 489 amino acid protein that shows strong expression in skeletal muscle; moderate expression in heart, small intestine, liver, pancreas, testis and colon; and lesser expression in brain, placenta, kidney, spleen, thymus, prostate, ovary and lymphocytes. DPH2 interacts with DPH1 and, functioning together as a dimer or multimer, DPH1 and DPH2 may participate in diphthamide biosynthesis. Diphthamide is a posttranslationally modified histidine residue which occurs in EF-2 (elongation factor 2) and targets diphtheria toxin ADP-ribosylation. The loss of DPH2 in Saccharomyces cerevisiae is believed to suppress zymocicity. Two transcript variants encoding different isoforms have been found for this gene.Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2.Tissue specificity:Strongly expressed in skeletal muscle. Moderately expressed in heart, small intestine, liver, pancreas, testis and colon. Weakly expressed in brain, placenta, kidney, speen, thymus, prostate, ovary and lymphocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1226R-A488

Anti-GPA33 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-1226R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1226R-A488
Beschreibung: The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319 amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213 amino acid extracellular region, a single transmembrane domain, and a 62 amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1163R-A555

Anti-DEFB1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-1163R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1163R-A555
Beschreibung: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1226R-HRP

Anti-GPA33 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-1226R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1226R-HRP
Beschreibung: The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319 amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213 amino acid extracellular region, a single transmembrane domain, and a 62 amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15472R-A647

Anti-HGD Rabbit Polyclonal Antibody (ALEXA FLUOR® 647)

Artikel-Nr: (BOSSBS-15472R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-15472R-A647
Beschreibung: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyse the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterised by urine that turns dark on standing and alkalinisation, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15472R-A488

Anti-HGD Rabbit Polyclonal Antibody (ALEXA FLUOR® 488)

Artikel-Nr: (BOSSBS-15472R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-15472R-A488
Beschreibung: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyse the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterised by urine that turns dark on standing and alkalinisation, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11388R-FITC

Anti-AAMP Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-11388R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11388R-FITC
Beschreibung: AAMP is a 434 amino acid immunoglobulin-like protein that contains 8 WD repeats. Expressed in endothelial cells, cytotrophoblasts and blood vessels, AAMP is thought to have a heparin-sensitive role in cell adhesion and cell migration. AAMP is strongly expressed in poorly differentiated colon adenocarcinoma cells, suggesting a role for AAMP in tumor progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8586R-CY7

Anti-GIPC-2 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-8586R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8586R-CY7
Beschreibung: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1226R-CY5.5

Anti-GPA33 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-1226R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1226R-CY5.5
Beschreibung: The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319 amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213 amino acid extracellular region, a single transmembrane domain, and a 62 amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1163R-CY5.5

Anti-DEFB1 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-1163R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1163R-CY5.5
Beschreibung: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
UOM: 1 * 100 µl
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