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Anti-NOMO1 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-11595R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11595R-CY7
Beschreibung: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11997R

Anti-DDAH1 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-11997R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11997R
Beschreibung: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11997R-A750

Anti-DDAH1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-11997R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11997R-A750
Beschreibung: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyses dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11621R-CY7

Anti-GUCA2A Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-11621R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11621R-CY7
Beschreibung: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8586R-A488

Anti-GIPC-2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-8586R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8586R-A488
Beschreibung: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11043R-CY5

Anti-BEST4 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-11043R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11043R-CY5
Beschreibung: Bestrophin-4 is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.
UOM: 1 * 100 µl
Product Image-7365-10

Engporige präparative Verpackungen, J.T. Baker® BAKERBOND®

Lieferant: Avantor
Beschreibung: Verpackungsmaterialien für die präparative Niederdruck- und Flash-Chromatographie. Chemisch stabil von pH 2 bis 8,5. Sie werden durch die Verwendung von Reinigungs- und antimikrobiellen Mitteln wie Natriumazid, verdünnte wässrige Lösungen von Trifluoressigsäure und Essigsäure, organische Lösungsmittel wie Methanol und Acetonitril sowie konzentrierte wässrige Lösungen von Salzen und Harnstoff nicht beschädigt. Die Verpackungen weisen unregelmäßig geformte Partikel auf.

Zertifikate

Image Unavailable-BOSSBS-11754R-CY5

Anti-SCGN Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-11754R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11754R-CY5
Beschreibung: SCGN is a 276 amino acid cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. Expressed in a variety of tissues including stomach, thyroid, colon, brain and neuroendocrine cells, SCGN is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11754R-CY7

Anti-SCGN Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-11754R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11754R-CY7
Beschreibung: SCGN is a 276 amino acid cytoplasmic protein that contains six EF-hand domains and is related to the calicium-binding proteins Calretinin and Calbindin D28K. Expressed in a variety of tissues including stomach, thyroid, colon, brain and neuroendocrine cells, SCGN is thought to be involved in cell proliferation and KCl (potassium chloride)-mediated calcium flux events. Through its interaction with KCl and its subsequent ability to modulate calcium storage pools within the cell, SCGN may function to negatively control growth and differentiation rates and, thus, indirectly inhibit cell replication.
UOM: 1 * 100 µl
Image Unavailable-BNC940891-500

Anti-MUC6 Mouse Monoclonal Antibody (CF594) [clone: CLH5]

Lieferant: Biotium
Beschreibung: The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

Image Unavailable-BOSSBS-1226R-A350

Anti-GPA33 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-1226R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1226R-A350
Beschreibung: The glycoprotein encoded by this gene is a cell surface antigen that is expressed in greater than 95% of human colon cancers. The open reading frame encodes a 319 amino acid polypeptide having a putative secretory signal sequence and 3 potential glycosylation sites. The predicted mature protein has a 213 amino acid extracellular region, a single transmembrane domain, and a 62 amino acid intracellular tail. The sequence of the extracellular region contains 2 domains characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8586R-CY5.5

Anti-GIPC-2 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-8586R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8586R-CY5.5
Beschreibung: GIPC2 is a 315 amino acid protein that localizes to the cytoplasm and contains one PDZ domain. Expressed at high levels in kidney and colon and at lower levels in adult liver, GIPC2 interacts with SEMA5A and is thought to function as a scaffold protein, possibly modulating cell adhesion and growth factor signaling and playing a role in tumorigenesis. The gene encoding GIPC2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11621R-CY3

Anti-GUCA2A Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-11621R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11621R-CY3
Beschreibung: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10kDa form is found circulating in the blood.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1163R-A488

Anti-DEFB1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-1163R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1163R-A488
Beschreibung: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. The mature form of Beta defensin 1 is 36 amino acids.
UOM: 1 * 100 µl
Image Unavailable-ROTHCP02.2

Acetonitril mit 0,1% (v/v) Trifluoressigsäure

Lieferant: Roth Carl
Beschreibung: Acetonitril mit 0,1% (v/v) Trifluoressigsäure

Image Unavailable-BOSSBS-11997R-A680

Anti-DDAH1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-11997R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11997R-A680
Beschreibung: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyses dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
UOM: 1 * 100 µl
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