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Image Unavailable-BOSSBS-2358R-HRP

Anti-FOXA2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-2358R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2358R-HRP
Beschreibung: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2358R-CY5.5

Anti-FOXA2 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-2358R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2358R-CY5.5
Beschreibung: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-2358R-A647

Anti-FOXA2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-2358R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2358R-A647
Beschreibung: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2358R-A750

Anti-FOXA2/HNF 3beta Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-2358R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2358R-A750
Beschreibung: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2358R-A680

Anti-FOXA2/HNF 3beta Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-2358R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2358R-A680
Beschreibung: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Image Unavailable-MDT100-1KT

Tissue Marking Dye Kit, Sigma-Aldrich®

Artikel-Nr: (MDT100-1KT)
Lieferant: SIGMA ALDRICH MICROSCOPY
Hersteller Artikel Nummer : MDT100-1KT
Beschreibung: Designed for orientation of excised surgical specimens. This method of permanently marking the margins of tissue specimens is very beneficial to surgeon and pathologists testing for skin cancer.
UOM: 1 * 1 KIT
Product Image-1.01603.0001

Gram-color Färbekit modifiziert zur Gramfärbung phenolfrei, Sigma-Aldrich®

Artikel-Nr: (1.01603.0001)
Lieferant: Merck
Hersteller Artikel Nummer : 1.01603.0001
Beschreibung: Phenol-free staining kit for the Gram staining method
UOM: 1 * 1 SET

Sicherheitsdatenblätter Zertifikate


Image Unavailable-BOSSBS-2358R-CY3

Anti-FOXA2 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-2358R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2358R-CY3
Beschreibung: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2358R-A555

Anti-FOXA2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-2358R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2358R-A555
Beschreibung: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Image Unavailable-ENZOBML28330100

Protease inhibitor library, Screen-Well®

Lieferant: ENZO LIFE SCIENCES
Beschreibung: The Screen-Well™ Protease Inhibitor Library includes 53 known protease inhibitors on a single 96-well plate. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 microliters per well. The library includes inhibitors to a broad range of important proteases and is a convenient and cost-effective way to purchase a panel of protease inhibitors for chemical genomics, assay development, and other applications. It includes inhibitors of: Calpains, TPPII, Neutrophil Elastase, Cathepsins, DPPIV, Caspases, Granzyme B, gamma-Secretase, Furin, MMPs, ACE, Kallikrein, Proteasome, Aminopeptidase B, and many more.

New Product

Product Image-1.50645.0001

UHPLC-Säulen, Purospher® STAR RP-18 endcapped

Lieferant: Merck
Beschreibung: Diese UHPLC-Säulen, die mit optimiertem 2-μm-Partikel-Kieselerde erhältlich sind und auf Purospher® STAR RP-18 mit Endcapping basieren, sind ideal für ultraschnelle Anwendungen, bei denen Auflösung, Empfindlichkeit und Probendurchsatz entscheidend sind. Sie sind die erste Wahl für Hochdurchsatz-Screening und QC-Analysen, Prozessüberwachung, Methodenentwicklung und LC-MS-Anwendungen. Aufgrund ihrer ausgewogenen Selektivität decken Purospher® STAR RP-18 UHPLC-Säulen mit Endcapping nahezu alle anspruchsvollen Trennungen mit Tailing-freien Chromatogrammen ab. Purospher® STAR RP-18 3-μm-Säulen mit Endcapping werden für schwierige Proben empfohlen, bei denen Verstopfung und Gegendruck ein Problem darstellen.

Sicherheitsdatenblätter

Image Unavailable-1.10307.0500

Reagenziensätze für die enzymatische Lebensmittelanalytik, Supelco®

Artikel-Nr: (1.10307.0500)
Lieferant: Merck
Hersteller Artikel Nummer : 1.10307.0500
Beschreibung: Test kit, Protein (Biuret-Methode bei 546 nm), Reagenzlösung für ca. 250 Bestimmungen
UOM: 1 * 500 mL

Sicherheitsdatenblätter Zertifikate


Image Unavailable-1.17179.0001

Visual colour kits, carbon dioxide, MQuant®

Artikel-Nr: (1.17179.0001)
Lieferant: Merck
Hersteller Artikel Nummer : 1.17179.0001
Beschreibung: Carbon dioxide is an important parameter for the assessment of the surface water quality and of the corrosive behavior of water. The kit is used for water and wastewater treatments following titrimetric method.
UOM: 1 * 1 ST
Image Unavailable-A-061-1.2ML

Multi-component alcohol mixtures for calibration, Cerilliant®, Supelco®

Lieferant: Merck
Beschreibung: Multi-component calibration kits containing acetone, ethanol, isopropanol, and methanol varying concentrations. These kits ares suitable for calibration of blood alcohol testing methods using GC Headspace.

Product Image-1.15973.0002

Eisenhämatoxylin Kit (Weigert's) Färbemittel für Histologie, Sigma-Aldrich®

Artikel-Nr: (1.15973.0002)
Lieferant: Merck
Hersteller Artikel Nummer : 1.15973.0002
Beschreibung: Nuclear staining in connective tissue staining methods
UOM: 1 * 2 ST

Sicherheitsdatenblätter


Image Unavailable-BOSSBS-8634R-HRP

Anti-FOXA1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-8634R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8634R-HRP
Beschreibung: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures into cell type-specific enhancer-driven transcriptional programs. Its differential recruitment to chromatin is dependent on distribution of histone H3 methylated at 'Lys-5' (H3K4me2) in estrogen-regulated genes. Involved in the development of multiple endoderm-derived organ systems such as liver, pancreas, lung and prostate; FOXA1 and FOXA2 seem to have at least in part redundant roles (By similarity). Modulates the transcriptional activity of nuclear hormone receptors. Is involved in ESR1-mediated transcription; required for ESR1 binding to the NKX2-1 promoter in breast cancer cells; binds to the RPRM promter and is required for the estrogen-induced repression of RPRM. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis.
UOM: 1 * 100 µl
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