Drucken

Sie suchten nach: ACTIVE+MOTIF


162'617  results were found

Suchergebnis einschränken: Sortieren nach
SearchResultCount:"162617"

Sort Results

Listenansicht Easy View

Bewerten Sie das Suchergebnis

Image Unavailable-BOSSBS-2727R-A350

Anti-CRLF2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-2727R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2727R-A350
Beschreibung: TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2727R-A488

Anti-CRLF2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-2727R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2727R-A488
Beschreibung: TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.
UOM: 1 * 100 µl

Neue Transparenz für europäische Kunden

Haben Sie an der Kasse unsere neue und verbesserte Sichtbarkeit des Lagerbestands bemerkt?

Weitere Informationen

Erweiterung der Lagerstandorte

Image Unavailable-BOSSBS-2727R-A750

Anti-CRLF2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-2727R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2727R-A750
Beschreibung: TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarisation of human Th2 memory T cells in allergic diseases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2727R-CY7

Anti-CRLF2 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-2727R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2727R-CY7
Beschreibung: TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13228R-HRP

Anti-FURIN Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-13228R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-13228R-HRP
Beschreibung: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7042R-CY3

Anti-ELF1 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-7042R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7042R-CY3
Beschreibung: E74 ike Factor 1 is a transcription factor that may be required for the T-cell receptor mediated activation of HIV2 gene expression. It binds to two purine-rich motifs in the HIV-2 enhancer and transcriptionally activates the LYN and mouse BLK promoters.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7042R-CY7

Anti-ELF1 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-7042R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7042R-CY7
Beschreibung: E74 ike Factor 1 is a transcription factor that may be required for the T-cell receptor mediated activation of HIV2 gene expression. It binds to two purine-rich motifs in the HIV-2 enhancer and transcriptionally activates the LYN and mouse BLK promoters.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5487R-A555

Anti-MAPK9 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-5487R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5487R-A555
Beschreibung: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5487R-A647

Anti-MAPK9 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-5487R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5487R-A647
Beschreibung: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11805R-FITC

Anti-ZFHX3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-11805R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11805R-FITC
Beschreibung: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (1–3). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).
UOM: 1 * 100 µl
Product Image-BOSSBS-11994R

Anti-Phosphoserine/threonine Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-11994R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11994R
Beschreibung: A hallmark of signal transduction pathways is the reversible phosphorylation of serine and threonine residues within specific sequences, or motifs, in target proteins. Specific signaling motifs include not only sequences that are recognized by protein kinases, but also those that are recognized by phosphorylation-dependent binding proteins like 14-3-3. These modular phosphoprotein interacting domains are critical elements in modulating, directing and amplifying intracellular communications. Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine surrounded by phenylalanine or tyrosine. For example, Akt, an important kinase that regulates cell survival, is activated by phosphorylation at Ser473, a site surrounded by phenylalanine and tyrosine. RSK1, p70 S6 K, and certain PKC isoforms also contain a similar consensus phosphorylation site. Phosphorylation of these sites is required for kinase activity. The (Ser/Thr) Phe Antibody is a powerful tool for discovery of new proteins containing this important regulatory motif.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5487R-CY7

Anti-MAPK9 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-5487R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5487R-CY7
Beschreibung: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
UOM: 1 * 100 µl
Image Unavailable-PRSI91-088

Human Recombinant Bc1-w (from E. coli)

Artikel-Nr: (PRSI91-088)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 91-088
Beschreibung: Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a docking site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
UOM: 1 * 0,05 mg

New Product


Image Unavailable-BOSSBS-6790R-A680

Anti-14-3-3 zeta/delta Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-6790R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-6790R-A680
Beschreibung: Adapter protein implicated in the regulation of a large spectrum of both general and specialised signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7042R-CY5.5

Anti-ELF1 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-7042R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7042R-CY5.5
Beschreibung: E74 ike Factor 1 is a transcription factor that may be required for the T-cell receptor mediated activation of HIV2 gene expression. It binds to two purine-rich motifs in the HIV-2 enhancer and transcriptionally activates the LYN and mouse BLK promoters.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1077R-CY5.5

Anti-POU2F2 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-1077R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1077R-CY5.5
Beschreibung: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
UOM: 1 * 100 µl
Inquire for Price
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Regulatory Affairs.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Das Produkt kann nicht in den Warenkorb gelegt werden.
Der Grund kann ein Preis auf Anfrage oder ein Artikelblock sein.
Bitte kontaktieren Sie Ihr zuständiges VWR Team für weitere Informationen
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Mit diesem Symbol gekennzeichnete Produkte werden nicht mehr angeboten - bis zum Ende des Lagerbestands verkauft. Alternativen können durch Suchen mit der oben aufgeführten VWR-Katalognummer verfügbar sein. Wenn Sie weitere Hilfe benötigen, rufen Sie bitte den VWR-Kundendienst an unter 044 745 13 13
49 - 64 of 162'617
no targeter for Bottom