Drucken

Sie suchten nach: ACTIVE+MOTIF


162'617  results were found

Suchergebnis einschränken: Sortieren nach
SearchResultCount:"162617"

Sort Results

Listenansicht Easy View

Bewerten Sie das Suchergebnis

Image Unavailable-ENZOADIKAPMA003E

Anti-MAPKK5 Rabbit Polyclonal Antibody

Artikel-Nr: (ENZOADIKAPMA003E)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : ADIKAPMA003E
Beschreibung: MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an increase in MAPK activity. MEK is involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis.
UOM: 1 * 100 µG

New Product


Image Unavailable-BOSSBS-9055R-CY5

Anti-DRAP1 Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-9055R-CY5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9055R-CY5
Beschreibung: DR1, also known as NC2∫ (negative cofactor 2 subunit ∫), is a TFIID (TATA box-binding protein)-associated protein. DR1 localizes to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated in vivo.
UOM: 1 * 100 µl

Neue Transparenz für europäische Kunden

Haben Sie an der Kasse unsere neue und verbesserte Sichtbarkeit des Lagerbestands bemerkt?

Weitere Informationen

Erweiterung der Lagerstandorte

Image Unavailable-BOSSBS-9055R

Anti-DRAP1 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-9055R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9055R
Beschreibung: DR1, also known as NC2∫ (negative cofactor 2 subunit ∫), is a TFIID (TATA box-binding protein)-associated protein. DR1 localizes to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated in vivo.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11805R-A680

Anti-ATBF1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-11805R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11805R-A680
Beschreibung: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer. Alternative splicing generates the ATBF1-A and ATBF1-B. While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains. Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs. The N-terminal extension unique to ATBF1-A has transcriptional repressor activity. In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element. Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity. ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs. ATBF1 is highly expressed in spleen and brain tissues. The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11805R-CY3

Anti-ZFHX3 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-11805R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11805R-CY3
Beschreibung: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (1–3). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11805R-CY7

Anti-ZFHX3 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-11805R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11805R-CY7
Beschreibung: AT-motif binding factor 1 (ATBF1) binds to the AT-rich core sequence element in the human a-fetoprotein enhancer (1). Alternative splicing generates the ATBF1-A and ATBF1-B (2,3). While ATBF1-A contains a 920-amino acid extension at the N-terminus, both ATBF1-A and ATBF1-B contain 4 DNA-binding homeobox domains (2,3). Additionally, ATBF1-A contains 23 zinc finger motifs while ATBF1-B contains 18 zinc finger motifs (1–3). The N-terminal extension unique to ATBF1-A has transcriptional repressor activity (4). In the small intestine, ATBF1-A inhibits expression of the brushborder enzyme aminopeptidase-N through direct binding to the AT motif element (5). Besides functioning in transcription regulation, ATBF1 also functions in ATPase activity (6). ATPase activity associated with ATBF1-A is DNA/RNA-dependent and requires both homeobox domains and zinc finger motifs (6). ATBF1 is highly expressed in spleen and brain tissues (7). The gene encoding human ATBF1 maps to chromosome 16q22.3-q23.1 (8).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2727R-A555

Anti-CRLF2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Artikel-Nr: (BOSSBS-2727R-A555)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2727R-A555
Beschreibung: TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7042R-CY3

Anti-ELF1 Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-7042R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7042R-CY3
Beschreibung: E74 ike Factor 1 is a transcription factor that may be required for the T-cell receptor mediated activation of HIV2 gene expression. It binds to two purine-rich motifs in the HIV-2 enhancer and transcriptionally activates the LYN and mouse BLK promoters.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7042R-CY7

Anti-ELF1 Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-7042R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-7042R-CY7
Beschreibung: E74 ike Factor 1 is a transcription factor that may be required for the T-cell receptor mediated activation of HIV2 gene expression. It binds to two purine-rich motifs in the HIV-2 enhancer and transcriptionally activates the LYN and mouse BLK promoters.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5487R-A350

Anti-MAPK9 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-5487R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5487R-A350
Beschreibung: phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5590R-CY5.5

Anti-YWHAE Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-5590R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-5590R-CY5.5
Beschreibung: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8054R-HRP

Anti-KLHL10 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-8054R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-8054R-HRP
Beschreibung: The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 44-56 amino acid repeat motif. The kelch motif appears in many different polypeptide contexts and contains multiple potential protein-protein contact sites. Members of this family are present both throughout the cell and extracellularly, with diverse activities.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9253R

Anti-RNF133 Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-9253R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9253R
Beschreibung: RNF133 contains a RING finger domain, a motif known to be involved in protein-protein and protein-DNA interactions. This gene has no intron. RNF133 may have E3 ubiquitin-protein ligase activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1077R-A750

Anti-2-Oct Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-1077R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1077R-A750
Beschreibung: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1077R-A680

Anti-2-Oct Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-1077R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1077R-A680
Beschreibung: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3210R-CY7

Anti-JUN Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-3210R-CY7)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-3210R-CY7
Beschreibung: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
UOM: 1 * 100 µl
Inquire for Price
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Regulatory Affairs.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Das Produkt kann nicht in den Warenkorb gelegt werden.
Der Grund kann ein Preis auf Anfrage oder ein Artikelblock sein.
Bitte kontaktieren Sie Ihr zuständiges VWR Team für weitere Informationen
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Mit diesem Symbol gekennzeichnete Produkte werden nicht mehr angeboten - bis zum Ende des Lagerbestands verkauft. Alternativen können durch Suchen mit der oben aufgeführten VWR-Katalognummer verfügbar sein. Wenn Sie weitere Hilfe benötigen, rufen Sie bitte den VWR-Kundendienst an unter 044 745 13 13
33 - 48 of 162'617
no targeter for Bottom