Drucken

Sie suchten nach: ACTIVE+MOTIF


163'021  results were found

Suchergebnis einschränken: Sortieren nach
SearchResultCount:"163021"

Sort Results

Listenansicht Easy View

Bewerten Sie das Suchergebnis

Image Unavailable-BOSSBS-11449R-A680

Anti-ABLIM1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-11449R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-11449R-A680
Beschreibung: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumours, thus identifying ABLIM1 as a candidate tumour suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localised on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho Signalling) dependent activation of serum-response factor (SRF), thereby modulating transcription.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12419R-CY3

Anti-YWHAQ Rabbit Polyclonal Antibody (Cy3®)

Artikel-Nr: (BOSSBS-12419R-CY3)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12419R-CY3
Beschreibung: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.This antibody is reactive with 14-3-3 Alpha/Beta/Gamma/Delta/Epsilon.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9055R-CY5.5

Anti-DRAP1 Rabbit Polyclonal Antibody (Cy5.5®)

Artikel-Nr: (BOSSBS-9055R-CY5.5)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9055R-CY5.5
Beschreibung: DR1, also known as NC2∫ (negative cofactor 2 subunit ∫), is a TFIID (TATA box-binding protein)-associated protein. DR1 localizes to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated in vivo.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9055R-A680

Anti-DR1 protein Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-9055R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9055R-A680
Beschreibung: DR1, also known as NC2 (negative cofactor 2 subunit ), is a TFIID (TATA box-binding protein)-associated protein. DR1 localises to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated <i>in vivo</i>.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9055R-A488

Anti-DRAP1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Artikel-Nr: (BOSSBS-9055R-A488)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9055R-A488
Beschreibung: DR1, also known as NC2∫ (negative cofactor 2 subunit ∫), is a TFIID (TATA box-binding protein)-associated protein. DR1 localizes to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated in vivo.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9055R-A647

Anti-DRAP1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-9055R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9055R-A647
Beschreibung: DR1, also known as NC2∫ (negative cofactor 2 subunit ∫), is a TFIID (TATA box-binding protein)-associated protein. DR1 localizes to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated in vivo.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9055R-A750

Anti-DR1 protein Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-9055R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-9055R-A750
Beschreibung: DR1, also known as NC2 (negative cofactor 2 subunit ), is a TFIID (TATA box-binding protein)-associated protein. DR1 localises to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated <i>in vivo</i>.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2727R-A647

Anti-CRLF2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-2727R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2727R-A647
Beschreibung: TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2727R-HRP

Anti-CRLF2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-2727R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2727R-HRP
Beschreibung: TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12419R-A750

Anti-1433T Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-12419R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12419R-A750
Beschreibung: Adapter protein implicated in the regulation of a large spectrum of both general and specialised Signalling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.This antibody is reactive with 14-3-3 Alpha/Beta/Gamma/Delta/Epsilon.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12419R-FITC

Anti-YWHAQ Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-12419R-FITC)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-12419R-FITC
Beschreibung: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.This antibody is reactive with 14-3-3 Alpha/Beta/Gamma/Delta/Epsilon.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1280R-A750

Anti-TCF7L2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-1280R-A750)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1280R-A750
Beschreibung: Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1280R-HRP

Anti-TCF7L2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Artikel-Nr: (BOSSBS-1280R-HRP)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-1280R-HRP
Beschreibung: Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2721R-A647

Anti-MCM5 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Artikel-Nr: (BOSSBS-2721R-A647)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2721R-A647
Beschreibung: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2721R-A680

Anti-MCM5 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-2721R-A680)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2721R-A680
Beschreibung: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2721R-A350

Anti-MCM5 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Artikel-Nr: (BOSSBS-2721R-A350)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2721R-A350
Beschreibung: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.
UOM: 1 * 100 µl
Inquire for Price
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 044 745 13 13.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Regulatory Affairs.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Das Produkt kann nicht in den Warenkorb gelegt werden.
Der Grund kann ein Preis auf Anfrage oder ein Artikelblock sein.
Bitte kontaktieren Sie Ihr zuständiges VWR Team für weitere Informationen
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Mit diesem Symbol gekennzeichnete Produkte werden nicht mehr angeboten - bis zum Ende des Lagerbestands verkauft. Alternativen können durch Suchen mit der oben aufgeführten VWR-Katalognummer verfügbar sein. Wenn Sie weitere Hilfe benötigen, rufen Sie bitte den VWR-Kundendienst an unter 044 745 13 13
177 - 192 of 163'021
no targeter for Bottom