Sie suchten nach: 8-(4-Chlorophenylthio)guanosine-3\',5\'-cyclic+monophosphate+sodi

Artikel-Nr: (AATB17105)

Lieferant: AAT BIOQUEST

Hersteller Artikel Nummer : 17105

Beschreibung: Cyclic adenosine monophosphate (cAMP) is a second messenger used for intracellular signal induction.

UOM: 1 * 100 µG

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Artikel-Nr: (AATB17102)

Lieferant: AAT BIOQUEST

Hersteller Artikel Nummer : 17102

Beschreibung: Cyclic adenosine monophosphate (cAMP) is a second messenger used for intracellular signal induction.

UOM: 1 * 1 mg

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Lieferant: AAT BIOQUEST

Beschreibung: Adenosine 3’, 5’ cyclic monophosphate (cAMP) is an important second messenger in intracellular signal transduction.

Artikel-Nr: (PRSI30-114)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 30-114

Beschreibung: PDE9A catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides.The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene.

UOM: 1 * 50 µG

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Artikel-Nr: (PRSI32-170)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 32-170

Beschreibung: The HPRT1 gene provides instructions for making an enzyme called hypoxanthine phosphoribosyltransferase 1. This enzyme allows cells to recycle purines, some of the building blocks of DNA and its chemical cousin RNA.The enzyme hypoxanthine-guanine phosphoribosyltrasferase (E.C.2.4.2.8., HPRT) plays a crucial role in uric acid synthesis and purine metabolism.This enzyme catalyzes the conversion of hypoxanthine and guanine to inosine monophosphate (IMP) and guanosine monophosphate (GMP), respectively, and uses phosphoribosylpyrophosphate (PRPP) as a cosubstrate and as a source of energy. This pathway is also known as the purine salvage pathway because it allows cells to reuse purine compounds to build DNA and RNA.

UOM: 1 * 100 µl

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Artikel-Nr: (TCIAD4228-25MG)

Lieferant: TCI

Hersteller Artikel Nummer : D4228-25MG

Beschreibung: Dibutyryl-cAMP sodium salt ≥97,0% (durch HPLC)

UOM: 1 * 25 mg

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Artikel-Nr: (PRSI55-781)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 55-781

Beschreibung: This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

UOM: 1 * 400 µl

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Artikel-Nr: (PRSI55-329)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 55-329

Beschreibung: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.

UOM: 1 * 400 µl

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Artikel-Nr: (PRSI56-074)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 56-074

Beschreibung: Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).

UOM: 1 * 400 µl

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Artikel-Nr: (PRSI91-320)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 91-320

Beschreibung: IGFBP-4, whose full name is insulin-like growth factor-binding protein 4, is induced by forskolin and N6, O2’dibutyryl sdenosine 3’, or 5’-cyclic monophosphate. It contains IGFBP N-terminal domain and thyroglobulin type-1 domain, and can bind IGF2. The IGF-binding proteins can prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.

UOM: 1 * 50 µG

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Artikel-Nr: (PRSI6633)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 6633

Beschreibung: EPAC2 Antibody: EPAC2, also known as Rap guanine nuclear exchange factor 4 and cAMPGEF-II, is belongs to a family of cyclic adenosine monophosphate (cAMP) binding proteins with guanine nucleotide exchange factor. Like the related protein EPAC1, EPAC2 signaling plays a role in numerous cellular processes such as integrin-mediated cell adhesion, muscle contraction, learning and memory, cell proliferation, and inflammation. Recent evidence suggests that EPAC2 induces synapse remodeling and depression, with mutations in its gene being found in patients with autism.

UOM: 1 * 100 µG

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Artikel-Nr: (PRSI34-037)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 34-037

Beschreibung: Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

UOM: 1 * 100 µG

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Artikel-Nr: (PRSI33-773)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 33-773

Beschreibung: Cystic fibrosis transmembrane conductance regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (MDR1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.

UOM: 1 * 100 µG

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Artikel-Nr: (8.41881.0001)

Lieferant: Merck

Hersteller Artikel Nummer : 8.41881.0001

Beschreibung: 2-(4-Chlorphenylthio)benzaldehyd zur Synthese

UOM: 1 * 1 g

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Artikel-Nr: (PRSI55-210)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 55-210

Beschreibung: Guanine nucleotide-binding protein (G protein) alpha subunit playing a prominent role in bitter and sweet taste transduction as well as in umami (monosodium glutamate, monopotassium glutamate, and inosine monophosphate) taste transduction. Transduction by this alpha subunit involves coupling of specific cell-surface receptors with a cGMP-phosphodiesterase; Activation of phosphodiesterase lowers intracellular levels of cAMP and cGMP which may open a cyclic nucleotide-suppressible cation channel leading to influx of calcium, ultimately leading to release of neurotransmitter. Indeed, denatonium and strychnine induce transient reduction in cAMP and cGMP in taste tissue, whereas this decrease is inhibited by GNAT3 antibody. Gustducin heterotrimer transduces response to bitter and sweet compounds via regulation of phosphodiesterase for alpha subunit, as well as via activation of phospholipase C for beta and gamma subunits, with ultimate increase inositol trisphosphate and increase of intracellular Calcium. GNAT3 can functionally couple to taste receptors to transmit intracellular signal: receptor heterodimer TAS1R2/TAS1R3 senses sweetness and TAS1R1/TAS1R3 transduces umami taste, whereas the T2R family GPCRs act as bitter sensors. Functions also as lumenal sugar sensors in the gut to control the expression of the Na+-glucose transporter SGLT1 in response to dietaty sugar, as well as the secretion of Glucagon-like peptide-1, GLP-1 and glucose-dependent insulinotropic polypeptide, GIP. Thus, may modulate the gut capacity to absorb sugars, with implications in malabsorption syndromes and diet-related disorders including diabetes and obesity.

UOM: 1 * 400 µl

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Lieferant: Thermo Fisher Scientific

Beschreibung: 2-(4-Chlorphenylthio)benzaldehyd ≥98%

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