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Artikel-Nr: (PRSI90-356)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 90-356
Beschreibung: Mitochondrial NMNAT isoform. Catalyses the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of nicotinic acid mononucleotide (NAMN) as substrate with the same efficiency. Can use tiazofurin monophosphate as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyses the reverse reaction, i. e. the pyrophosphorolytic cleavage of NAD+. For the pyrophosphorolytic activity, mitochondrial NMNAT isoform can use NAD(+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NAADP+. Protects against axonal degeneration following injury.
UOM: 1 * 10 µG


Lieferant: Merck Millipore (Calbiochem‎)
Beschreibung: β-Nicotinamid-Adenin-Dinucleotid Dinatriumsalz, reduzierte Form (NADH-Na₂), Millipore®

Artikel-Nr: (APOSBIB3013-1G)
Lieferant: Apollo Scientific
Hersteller Artikel Nummer : BIB3013-1G
Beschreibung: β-Nicotinamide adenine dinucleotide phosphate sodium salt hydrate ≥98% (oxidised form)
UOM: 1 * 1 g


Lieferant: Thermo Fisher Scientific
Beschreibung: β-Nicotinamid-Adenin-Dinucleotid Dinatriumsalz, reduzierte Form (NADH-Na₂) Hydrat 95+%, reduziert
Lieferant: Thermo Fisher Scientific
Beschreibung: ß-Nicotinamid-Adenin-Dinucleotid-Phosphat Tetranatriumsalz Hydrat, reduzierte Form (NADPH-Na4) 96%, reinst
Lieferant: PanReac AppliChem
Beschreibung: ß-Nicotinamid-Adenin-Dinucleotid-Phosphat Tetranatriumsalz, reduzierte Form (NADPH-Na4)
Lieferant: VWR Chemicals
Beschreibung: β-Nicotinamid-Adenin-Dinucleotid Dinatriumsalz, reduzierte Form (NADH-Na₂) Trihydrat, Reagenzqualität
Artikel-Nr: (PRSI36-169)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 36-169
Beschreibung: Processes such as transcription, repair and replication that require efficient DNA recognition are dependent on modulation of chromatin structure. Chromatin relaxation is a critical event that occurs during DNA repair and is associated with the negatively charged polymer of adenosine 5'-diphosphate (ADP)-ribose (PAR). PAR is synthesized from nicotinamide adenine dinucleotide (NAD+) by the poly(ADP-ribose) polymerase protein family (PARPs), of which PARP-1 (and to a lesser extent PARP-2) respond to DNA-strand breaks. PARP-1 is selectively activated by DNA strand breaks to catalyze the addition of long branched chains of PAR to a variety of nuclear proteins, most notably PARP itself. The amount of PAR formed in living cells with DNA damage is commensurate with the extent of the damage. Under DNA damage conditions, PAR undergoes a rapid turnover, with a half-life in the range of minutes, as PAR is rapidly hydrolyzed and converted to free ADP-ribose by the enzyme poly(ADP-ribose)glycohydrolase (PARG). PAR regulates not only cell survival and cell-death programmes, but also an increasing number of other biological functions with which novel members of the PARP family have been associated. These include transcriptional regulation, cell division, intracellular trafficking, inflammation and energy metabolism.
UOM: 1 * 100 µG


Artikel-Nr: (BOSSBS-2888R)
Lieferant: Bioss
Hersteller Artikel Nummer : BS-2888R
Beschreibung: Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
UOM: 1 * 100 µl


Artikel-Nr: (PRSI90-010)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 90-010
Beschreibung: Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
UOM: 1 * 50 µG


Artikel-Nr: (PRSI90-053)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 90-053
Beschreibung: Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
UOM: 1 * 50 µG


Lieferant: Apollo Scientific
Beschreibung: Purity determined enzymatic method (ADH).

Artikel-Nr: (PRSI90-018)
Lieferant: ProSci Inc.
Hersteller Artikel Nummer : 90-018
Beschreibung: Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
UOM: 1 * 10 µG


Lieferant: MP Biomedicals
Beschreibung: Nicotinamide adenine dinucleotide phosphate (NADP) and NADPH form a redox pair. NADP/NADPH is a coenzyme that supports redox reactions via the transport of electrons in a vast array of applications, especially anaerobic reactions such as lipid and nucleic acid synthesis. NADP/NADPH is a coenzyme couple in various cytochrome P450 systems and oxidase/reductase reaction systems, such as the thioredoxin reductase/thioredoxin system. This product will meet or exceed NRC specifications.

Lieferant: Thermo Fisher Scientific
Beschreibung: β-Nicotinamid-Adenin-Dinucleotid Dinatriumsalz, reduzierte Form (NADH-Na₂) 97%
Artikel-Nr: (ENZOBMLKI2820500)
Lieferant: ENZO LIFE SCIENCES
Hersteller Artikel Nummer : BMLKI2820500
Beschreibung: Cellular assay, Nicotinamide adenine dinucleotide (oxidised form) in 50 mM Tris/HCl and sirutin substrate
UOM: 1 * 500 µl


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