Sie suchten nach: Antikörper

Artikel-Nr: (BOSSBS-11510R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11510R

Beschreibung: 31472488

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-11506R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11506R

Beschreibung: Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. Other associated clinical findings in BBS patients include diabetes, hypertension, and congenital heart defects. BBS is a heterogeneous disorder that maps to eight genetic loci and encodes eight proteins, BBS1-BBS8. Five BBS genes encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS2 is a 721-amino acid protein that is evolutionarily conserved and is expressed in a broad range of tissues including: brain, kidney, adrenal gland, and thyroid gland. Loss of BBS2 may be involved in defects in social interactions as well as infertility. BBS2 retinopathy involves normal retina development followed by apoptotic death of photoreceptors, the primary ciliated cells of the retina.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-10152R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10152R

Beschreibung: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-10162R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10162R

Beschreibung: Binds free retinal and cellular retinol-binding protein-bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-10161R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10161R

Beschreibung: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-10141R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-10141R

Beschreibung: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (AGRIAS101190)

Lieferant: Agrisera

Hersteller Artikel Nummer : AS101190

Beschreibung: 31472488

UOM: 1 * 2 mg

Sale

Artikel-Nr: (AGRIAS101184)

Lieferant: Agrisera

Hersteller Artikel Nummer : AS101184

Beschreibung: 31472488

UOM: 1 * 1 mg

Sale

Artikel-Nr: (BOSSBS-5785R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5785R

Beschreibung: 31472488

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-6016R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6016R

Beschreibung: 31472488

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-5954R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5954R

Beschreibung: 31472488

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1252R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1252R

Beschreibung: Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-12537R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12537R

Beschreibung: ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1255R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1255R

Beschreibung: Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Required for normal ear development (By similarity).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-11840R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11840R

Beschreibung: 31472488

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-12533R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-12533R

Beschreibung: Required for V(D)J recombination, the process by which exons encoding the antigen-binding domains of immunoglobulins and T-cell receptor proteins are assembled from individual V, (D), and J gene segments. V(D)J recombination is initiated by the lymphoid specific RAG endonuclease complex, which generates site specific DNA double strand breaks (DSBs). These DSBs present two types of DNA end structures: hairpin sealed coding ends and phosphorylated blunt signal ends. These ends are independently repaired by the non homologous end joining (NHEJ) pathway to form coding and signal joints respectively. This protein exhibits single-strand specific 5'-3' exonuclease activity in isolation and acquires endonucleolytic activity on 5' and 3' hairpins and overhangs when in a complex with PRKDC. The latter activity is required specifically for the resolution of closed hairpins prior to the formation of the coding joint. May also be required for the repair of complex DSBs induced by ionizing radiation, which require substantial end-processing prior to religation by NHEJ.

UOM: 1 * 100 µl

Sale