Iodacetamid 98% stabilisiert
Lieferant: Thermo Scientific
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Gefahr
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Synonyms:
Iodessigsäureamid
Stabilization:
Angefeuchtet mit Wasser ∼5-8%
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation.
2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.
Formel:
ICH₂CONH₂ MW: 184,96 g/mol Siedepunkt: 266 °C (1013 hPa) Melting Pt: 92…95 °C (getrocknet) Lager Temperatur: Kühlschrank |
MDL Number:
MFCD00008028 CAS-Nummer: 144-48-9 EINECS: 205-630-1 UN: 2811 ADR: 6.1,III |
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