Hydrocortison ≥97%, weißes Pulver
Lieferant: ICN Biomedicals
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Achtung
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Synonyms:
11β,17α,21-Trihydroxypregn-4-en-3,20-dion
, 11β-Hydroxycortison
, 11β,17α,21-Trihydroxy-4-pregnen-3,20-dion
, Cortisol
Hydrocortisone, a primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency. Hydrocortisone, known more formally as cortisone (INN, USAN, BAN), is a steroid hormone, produced by the zona fasciculata of the adrenal gland. It is released in response to stress and a low level of blood glucocorticoids.
Hydrocortisone's primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. It also decreases bone formation. Various synthetic forms of cortisol are used to treat a variety of diseases.
Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.
Soluble (mg/ml) at 25 °C in: water 0,28; ethanol 15,0; methanol 6,2; acetone 9,3; chloroform 1,6; propylene glycol 12,7; ether ~ 0,35. Soluble in concentrated sulphuric acid with intense green fluorescence. Typical stock solutions can be prepared at concentrations of 50-500 mg solid (total powder) in 1 ml water
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Formel:
C₂₁H₃₀O₅ MW: 362,47 g/mol Siedepunkt: 567 °C (1013 hPa) Melting Pt: 202 - 204 °C Dichte: 1,4 g/cm³ (20 °C) |
MDL Number:
MFCD00011654 CAS-Nummer: 50-23-7 EINECS: 200-020-1 |
Spezifikation Testergebnisse
| Identity Test | Passes |
| Purity | ≥97% |
| FTIR | Conforms to Standard |
| Melting Point | 205 - 222 °C |
| Loss on Drying | ≤1% |
| UV/VIS: l max | 241 ± 3 nm (methanol) |
| Optical Rotation | 160 ±10° (c=1, methanol) |
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