Diphenylborsäure(2-aminoethyl)ester (2-APB) ≥98% (durch HPLC)

Lieferant: ENZO LIFE SCIENCES AG

ENZOALX400045M100EA 59.2 CHF
ENZOALX400045M100
Diphenylborsäure(2-aminoethyl)ester (2-APB) ≥98% (durch HPLC)
Diphenylborsäure(2-aminoethyl)ester (2-APB)

Cell permeable modulator of Ins(1,4,5)-P3-induced Ca²⁺ release. A prototype drug for a group of structurally related calcium channel blockers in human platelets. Has been shown, in the absence of other stimuli, to activate TRPV1, V2 and V3, but not TRPV4, V5 and V6 expressed in HEK 293 cells. Potentiates the effect of capsaicin, protons and heat on TRPV1. It was originally introduced as an IP3 receptor blocker and subsequently as an inhibitor of store-operated Ca²⁺ entry (75µM).


  • TRP channel activator


White to off-white crystalline solid.


Soluble in DMSO (20 mg/ml), dimethyl formamide (20 mg/ml) or 100% ethanol (5 mg/ml); slightly soluble in PBS, pH 7.2 (50 μg/ml).

Formel: C₁₄H₁₆BNO
MW: 225,1 g/mol
Lager Temperatur: Gefrierschrank
MDL Number: MFCD00014823
CAS-Nummer: 524-95-8
EINECS: 208-366-5

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