Vinblastine sulphate ≥98%
Lieferant: ENZO LIFE SCIENCES AG
ENZOALX350257M025EA
421
CHF
ENZOALX350257M025
Vinblastine sulphate ≥98%
Vinblastine sulphate
Cell cycle blocker
Plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Inhibits normal microtubule asembly and causes aberant tubulin polymerization. Blocks binding of tubulin to microtubule proteins. Induces apoptosis. Triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins and induction of p53 expression. Cancer chemotherapeutic agent.
Semisynthetic from catharanthine or vindoline.
Formel:
C₄₆H₆₀N₄O₁₃S |
MDL Number:
MFCD00082457 CAS-Nummer: 143-67-9 |
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