PPM1B Human siRNA Oligo Duplex (Locus ID 5495)

Lieferant: OriGene
ORIGSR303668EA 789 CHF
ORIGSR303668
PPM1B Human siRNA Oligo Duplex (Locus ID 5495)
Nukleinsäure-Reagenzien RNAi
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways.

  • Stability: One year from date of shipment when stored at −20 °C
  • Quality control: Tested by ESI-MS
  • Purity: HPLC purified
  • UniProt ID: O75688

This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Single siRNA duplex (10 nmol) can be ordered.

Number of transfections: Approximately 330 transfections/2 nmol in 24-well plate under optimized conditions (final conc. 10 nM).
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