DSG (Disuccinimidyl glutarate), Pierce™
Lieferant: Thermo Fisher Scientific
Synonyms:
Di(N-succinimidyl) glutarate, Bis(2,5-dioxopyrrolidin-1-yl) glutarate, DSG Crosslinker, DSG
Thermo Scientific Pierce DSG is a water-insoluble, homo-bifunctional N-hydroxysuccinimide ester (NHS-ester) crosslinker often used for conjugating radiolabeled ligands to cell-surface receptors. The NHS ester is the simplest and most commonly used reactive group for crosslinking and labeling proteins and peptides. NHS esters react with primary amines on the N-termini of peptides and the amine of lysine residues, forming a stable, covalent amide bond and releasing the NHS group.
- Reactive groups: NHS ester (both ends)
- Reactive towards: amino groups (primary amines)
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO)
- Membrane-permeable, allowing for intracellular crosslinking
- Can increase crosslinking efficiency compared to DSS in some applications
Thermo Scientific No-Weigh products are specialty reagents provided in a pre-aliquoted format. The pre-weighed packaging prevents the loss of reagent reactivity and contamination over time by eliminating the repetitive opening and closing of the vial. The format enables use of a fresh vial of reagent each time, eliminating the hassle of weighing small amounts of reagents and reducing concerns over reagent stability.
Bitte beachten For Research Use Only. Not for use in diagnostic procedures.
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Formel:
C₁₃H₁₄N₂O₈ MW: 326,26 g/mol Lager Temperatur: Kühlschrank |
MDL Number:
MFCD00153597 CAS-Nummer: 79642-50-5 |
Spezifikation Testergebnisse
| Product Line | Pierce™ |
| Labeling Method | Chemical Labeling |
| Crosslinker Type | Homobifunctional |
| Reactive Moiety | NHS Ester |
| Spacer | Short |
| Form | Powder |
| Quantity | 50 mg/10 x 1 mg |
| Type | Crosslinker |
| Solubility | DMF, DMSO |
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