GMBS (N-Succinimidyl 4-maleimidobutyrate), Pierce™
Lieferant: Thermo Fisher Scientific
Synonyms:
GMBS
Pierce™
PIER22309EA
306
CHF
PIER22309
GMBS (N-Succinimidyl 4-maleimidobutyrate), Pierce™
GMBS (N-Succinimidyl 4-maleimidobutyrate)
Thermo Scientific Pierce GMBS is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a short spacer arm (7.3 angstroms).
- Reactive groups: NHS ester and maleimide
- Reactive toward: amino and sulfhydryl groups
- C4-homolog of aliphatic spacer series which includes AMAS, BMPS, GMBS and EMCS
- NHS ester end couples with primary amines at pH 7-9 to form stable amide bonds
- Maleimides react with -SH groups at pH 6.5-7.5, forming stable thioether linkages
- Non-cleavable
- Water-insoluble (dissolve first in DMF or DMSO); compare to Sulfo-GMBS
- Short aliphatic spacer has low potential for eliciting an immune response
Bitte beachten For Research Use Only. Not for use in diagnostic procedures.
Formel:
C₁₂H₁₂N₂O₆ MW: 280,24 g/mol Lager Temperatur: Kühlschrank |
MDL Number:
MFCD00036817 CAS-Nummer: 80307-12-6 |
Spezifikation Testergebnisse
Product Line | Pierce™ |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Reactive Moiety | Maleimide, NHS Ester |
Spacer | Short |
Form | Solid |
Quantity | 50 mg |
Type | Crosslinker |
Solubility | DMF, DMSO |
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