Curcumin ≥99,5% (durch HPLC) Matrixsubstanz für MALDI-MS, Supelco®
Lieferant: Merck
A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Curcumin has been cited as a potential chemopreventive agent, in addition to its chemotherapeutic activity. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IκB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope.
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Formel:
C₂₁H₂₀O₆ MW: 368,39 g/mol Melting Pt: 183…188 °C Lager Temperatur: Kühlschrank |
MDL Number:
MFCD00008365 CAS-Nummer: 458-37-7 |
Spezifikation Testergebnisse
| Appearance (Color) | Yellow to Very Dark Yellow and Orange to Very Dark Orange |
| Appearance (Form) | Powder or Crystals |
| Purity (HPLC area %) | ≥ 99.5 % |
| Melting Point | 183 - 188 C |
| Carbon Content | 68.47 % (theory) |
| Hydrogen Content | 5.47 % (theory) |
| Proton NMR Spectrum | Conforms to structure |
| Metal trace Analysis (ICP) | Corresponds to requirements |
| BARIUM (ICP) | ≤ 5 mg/kg |
| CALCIUM (ICP) | ≤ 100 mg/kg |
| CADMIUM (ICP) | ≤ 5 mg/kg |
| COBALT (ICP) | ≤ 5 mg/kg |
| CHROMIUM (ICP) | ≤ 5 mg/kg |
| COPPER (ICP) | ≤ 5 mg/kg |
| IRON (ICP) | ≤ 30 mg/kg |
| POTASSIUM (ICP) | ≤ 50 mg/kg |
| MAGNESIUM (ICP) | ≤ 30 mg/kg |
| MANGANESE (ICP) | ≤ 5 mg/kg |
| SODIUM (ICP) | ≤ 50 mg/kg |
| NICKEL (ICP) | ≤ 5 mg/kg |
| LEAD (ICP) | ≤ 5 mg/kg |
| ZINC (ICP) | ≤ 5 mg/kg |
| RECOMMENDED RETEST PERIOD | 36 MONTHS |
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