Phorbol-12-myristate-13-acetate 95%
Lieferant: Thermo Scientific
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Achtung
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Synonyms:
TPA, Phorbol 12-myristate 13-acetate, 12-O-Tetradecanoylphorbol 13-acetate, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate, (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-Acetoxy-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl tetradecanoate
PMA activates Ca2+ - ATPase and potentiates forskolin-induced cAMP formation. Used to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.
Very soluble in methanol, soluble in DMSO, chloroform, ethanol or acetone, ether, ethyl acetate, DMF or acetonitrile. Insoluble in water.
Bitte beachten Light sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
Formel:
C₃₆H₅₆O₈ MW: 616,836 g/mol |
MDL Number:
MFCD00036736 CAS-Nummer: 16561-29-8 |
Spezifikation Testergebnisse
Appearance (Color) | White to pale cream |
Form | Powder, film or foam, solid |
Assay from Suppliers CofA | ≥94.0% |
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