Protamine sulphate (aus Lachssperma), ≥100 USP u/mg, weißes Pulver Reagenz für die Zellkultur
Lieferant: ICN Biomedicals
Synonyms:
Salmine sulphate
Storage: Room Temperature, desiccate
Protamine sulfate is a purified mixture of simple protein principles obtained from the sperm or testes of suitable species of fish, which has the property of neutralizing heparin. Because of having many basic amino acids (mostly arginine) protamine contains far greater nitrogen than other proteins. Its molecular weight is relatively small. Histone and other basic proteins in the testes of unmatured fishes convert into protamine along with the growth of the fishes. In the testes, protamine takes the form of nucleoprotamine linked with DNA.
Protamine Sulfate is a raw material for study preparations like insulin compounds, and etc. It is used in separation and refining of vaccines. It is a reagent for removing nucleic acids from enzyme solution for the purpose of easy separation and refining. Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Inhibits lipoprotein lipase. Protamine sulfate shown to inhibit the classical pathway of complement. It inhibits turnover of lipoproteins by lipoprotein lipase.
- Cell Culture Reagent Grade
- Presentation: White Powder
- Freely soluble in hot water, slightly soluble in cold water; soluble in 0.1 M KH2PO4; Soluble in HCl. Practically insoluble in organic solvents.
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Lager Temperatur:
Raumtemperatur |
MDL Number:
MFCD00132091 CAS-Nummer: 9009-65-8 |
Spezifikation Testergebnisse
| Identity Test | Passes |
| Source | Salmon Sperm |
| Loss on Drying | ≤5% |
| Sulfate | 16-22% |
| Nitrogen | 22.5-25.5% |
| Activity | ≥100 USP u/mg |
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