Thapsigargin ≥97% (durch TLC), farbloser Feststoff, Millipore®

Lieferant: Merck Millipore Calbiochem

586005-1EA 367 CHF
586005-1
Thapsigargin ≥97% (durch TLC), farbloser Feststoff, Millipore®
Thapsigargin

Thapsigargin is a cell-permeable tumour-promoting sesquiterpene lactone that releases Ca²⁺ by inhibiting endoplasmic reticular Ca²⁺-ATPase.


  • Colourless solid


It does not increase inositol phosphates and has no significant effect on protein kinase C. It increases Ca²⁺-dependent Na⁺ influx in human platelets in a dose-dependent manner. Ii induces apoptosis in rat thymocytes and in human hepatoma cells and in alveolar rhabdomyosarcoma cells by elevating Akt-stimulated PAX3-FOXO1 phosphorylation and promoting its proteasomal degradation.

Formel: C₃₄H₅₀O₁₂
MW: 650,762 g/mol
Lager Temperatur: Gefrierschrank
MDL Number: MFCD00083511
CAS-Nummer: 67526-95-8

Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR