FTY720 phosphate

Lieferant: Cayman Chemical

CAYM10008639-25EA 3650 CHF
CAYM10008639-25 CAYM10008639-5 CAYM10008639-10 CAYM10008639-1
FTY720 phosphate
FTY720 phosphate

FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.


  • Crystalline solid
  • Purity ≥98%
  • Stability: ≥2 years at −20 °C


In vivo, FTY720 is phosphorylated by sphingosine kinase to the physiologically active phosphoric acid ester. FTY720 phosphate acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4 and S1P5), with IC50 values of 0,2 to 6 nm

CAS-Nummer: 402615-91-2

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