Anti-DPP4 Mouse Monoclonal Antibody (CF568) [clone: 202-36]

Lieferant: Biotium

BNC680888-500EA 636 CHF
BNC680888-500 BNC680888-100
Anti-DPP4 Mouse Monoclonal Antibody (CF568) [clone: 202-36]
Antikörper
Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI; Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

Type: Primary
Antigen: DPP4
Clonality: Monoclonal
Clone: 202-36
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Human, Rat
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