Anti-CD44 Mouse Monoclonal Antibody (CF568) [clone: 156-3C11]

Lieferant: Biotium
BNC680460-500 BNC680460-100
BNC680460-500EA 671 CHF
BNC680460-500 BNC680460-100
Anti-CD44 Mouse Monoclonal Antibody (CF568) [clone: 156-3C11]
Antikörper
Recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. This MAb selectively interferes with lymphocyte binding to lymph node, mucosal and synovial endothelium. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.

Type: Primary
Antigen: CD44
Clonality: Monoclonal
Clone: 156-3C11
Conjugation: CF568
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Baboon, Green monkey, Human
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