Anti-CD33 Mouse Monoclonal Antibody (CF568) [clone: C33/69]

Lieferant: Biotium
BNC680069-500 BNC680069-100
BNC680069-500EA 671 CHF
BNC680069-500 BNC680069-100
Anti-CD33 Mouse Monoclonal Antibody (CF568) [clone: C33/69]
Antikörper
Recognizes a 67 kDa glycoprotein, which is identified as CD33. It is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acuteMore Product Information
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