2-Methyl-5-nitroimidazole-1-ethanol, weißes Pulver
Lieferant: ICN Biomedicals
Metronidazole ia an antiprotozoal (Trichomonas), a limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria.
Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that Metronidazole has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antibiotic is that it affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori which is resistant to Metronidazole.
Soluble in water (10 mg/ml) or dilute acids (50 mg/ml 0,1 M acetic acid - clear to slightly hazy, light yellowish-green solution); slightly soluble in ethanol (5 mg/ml).
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Formel:
C₆H₉N₃O₃ MW: 171,16 g/mol Melting Pt: 158…160° C (Lit.) Lager Temperatur: Kühlschrank |
MDL Number:
MFCD00009750 CAS-Nummer: 443-48-1 |
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