Vinblastine sulphate, weißes Pulver

Lieferant: ICN Biomedicals

ICNA0219028705EA 183 CHF
ICNA0219028705 ICNA0219028725 ICNA0219028701 ICNA0219028710
Vinblastine sulphate, weißes Pulver
Vinblastine sulphate

Vinblastine Sulphate is an anti-tumor alkaloid.


  • An anti-tumor alkaloid
  • Depolymerises microtubules.
  • Used in cancer research


Plant alkaloid that inhibits microtubule assembly by binding tubulin and inducing self-association in spiral aggregates in a reaction that appears to be regulated by the C-terminus of β-tubulin and is enhanced by GDP and GTP.


Arrests the cell cycle in G2/M-phase by blocking mitotic spindle formation. Triggers Raf-1 activation, phosphorylation of bcl-2-family proteins, induction of p53 expression, and apoptosis in several tumor cell lines. Substrate of Pgp and CYP3A4.


Very slightly soluble in ethanol. Practically insoluble in ether. One part is sol in 10 parts of water, 50 parts of chloroform.

Formel: C₄₆H₆₀N₄O₁₃S
MDL Number: MFCD00082457
CAS-Nummer: 143-67-9

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