Pegylation reagent, MT(PEG)₄ methyl-PEG-thiol compound

Lieferant: Thermo Fisher Scientific
PIER26132EA 487 CHF
PIER26132
Pegylation reagent, MT(PEG)₄ methyl-PEG-thiol compound
Protein-Aufbereitungs Proteinreinigungs-Reagenzien
Methyl-PEG4-thiol is a methyl- and sulfhydryl-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magnetic particles.

  • PEG groups are flexible, non-immunogenic and hydrophilic
  • Terminal monodentate thiol reacts spontaneously with gold surfaces through dative binding
  • Terminal methyl group coats quantum dot and other surfaces to reduce nonspecific binding in assays

The use of MT(PEG)4 with CT(PEG)12 in surface modification can form a hydrophilic "lawn" of methyl ether-terminated PEGs with periodic exposed carboxylic acid-containing PEGs. The exposed carboxylic acid groups can be coupled to affinity ligands using the carbodiimide coupling reaction with EDC and sulpho-NHS.
Order Now

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR