Anti-KIT Rat Monoclonal Antibody [clone: ACK2]

Lieferant: Tonbo Biosciences
40-1172-U500 40-1172-U100
40-1172-U500EA 323 CHF
40-1172-U500 40-1172-U100
Anti-KIT Rat Monoclonal Antibody [clone: ACK2]
Antikörper
The ACK2 antibody is specific for CD117, also called c-Kit, a 145 kDa cytokine receptor important in the development of hematopoietic stem cells, in oogenesis, and for functional activity of immune cells such as NK and mast cells. c-Kit binds to a ligand known as stem cell factor (SCF), or alternatively as mast cell growth factor. Ligand binding promotes the activation (dimerization) and subsequent tyrosine kinase activity of the c-Kit receptor and triggers key survival, expansion and maturation signals during hematopoietic progenitor cell development. Conversely, shedding of extracellularMore Product Information
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