Anti-CD4 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: GK1.5]

Lieferant: Tonbo Biosciences
20-0041-U100 20-0041-U025
20-0041-U100EA 174 CHF
20-0041-U100 20-0041-U025
Anti-CD4 Rat Monoclonal Antibody (APC (Allophycocyanin)) [clone: GK1.5]
Antikörper
The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

The GK1.5 antibody isMore Product Information
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TECHNISCHE DATEN

Antigen-Symbol CD4
Antigen-Name CD4 molecule
Environmentally Preferable
Antigen-Synonyme L3T4|p55|CD4mut|Ly-4|W3/25
Antikörper-Typ Primär
Klonalität Monoklonal
Konjugation APC (Allophycocyanin)
Klon GK1.5
Reaktivität Syrian hamster,Mouse
Wirt Rat
Gen-ID 12504
Isotyp IgG2b kappa
ImmunoChemie Yes
Immunpräzipitation Yes
Durchflusszytometrie Yes
Neutralisation Yes
Kreuzadsorption none
Lagertemperatur Cool
Transporttemperatur Ice
Validierte Anwendungen Flow Cytometry

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