6-Aminonicotinamid, blassgelbes kristallines Pulver

Lieferant: ICN Biomedicals
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ICNA0215010301EA 195 CHF
ICNA0215010301 ICNA0215010305
6-Aminonicotinamid, blassgelbes kristallines Pulver
6-Aminonicotinamid

6-Aminonicotinamide was found to inhibit NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase.


6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells (IC50 = 0.5 mM). 6-AN also reduces cardiovascular oxidative injury following ischemia/reperfusion. In addition, 6-AN causes glial neurodegeneration.

Formel: C₆H₇N₃O
MW: 137,14 g/mol
Lager Temperatur: Raumtemperatur
MDL Number: MFCD00006327
CAS-Nummer: 329-89-5
EINECS: 206-349-7

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Spezifikation Testergebnisse

Identity Test Passes
FTIR Conforms to Standard
Melting Point 240 - 250 °C

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