6-Aminonicotinamid, blassgelbes kristallines Pulver
Lieferant: ICN Biomedicals
|
Gefahr
|
ICNA0215010301EA
195
CHF
ICNA0215010301
ICNA0215010305
6-Aminonicotinamid, blassgelbes kristallines Pulver
6-Aminonicotinamid
6-Aminonicotinamide was found to inhibit NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase.
6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells (IC50 = 0.5 mM). 6-AN also reduces cardiovascular oxidative injury following ischemia/reperfusion. In addition, 6-AN causes glial neurodegeneration.
Formel:
C₆H₇N₃O MW: 137,14 g/mol Lager Temperatur: Raumtemperatur |
MDL Number:
MFCD00006327 CAS-Nummer: 329-89-5 EINECS: 206-349-7 |
Spezifikation Testergebnisse
Identity Test | Passes |
FTIR | Conforms to Standard |
Melting Point | 240 - 250 °C |
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