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Reducing particle sizes in liquids, the ultrasonic cell disrupters improve the overall uniformity and stability of mixtures. Using various homogenizing methods, the mechanical processing equipment evenly distributes particles to produce substances that yield consistent testing results. The ultrasonic cell disrupters are effective for DNA/RNA shearing, homogenization, cell lysis, nanoparticle dispersion, protein extraction, and general sample preparation. Internal circuitry guarantees efficient operation, sample-to-sample consistency, and a reliable end result.