Artikel-Nr: (PALB2-LAD-NM)

Lieferant: Palbam

Hersteller Artikel Nummer : 2-LAD-NM

Beschreibung: These step stools are designed for fixed locations where they are not required to be moved often.

UOM: 1 * 1 ST

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Artikel-Nr: (BOSSBS-11861R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11861R-CY7

Beschreibung: HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.

UOM: 1 * 100 µl

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Lieferant: Avantor Fluid Handling

Beschreibung: Kein Verstopfen oder Verschleiß – keine beweglichen Teile.

Lieferant: VWR Collection

Beschreibung: Entwickelt, um mehrere Reagenzgläser, Reagenzglasgestelle, Fläschchen oder Zylinder zu halten. Die Wirbelwirkung wird erzeugt, indem die Oberseite des Gefäßes an Ort und Stelle gehalten wird, während sich die Unterseite frei in einer definierten Umlaufbahn bewegen kann. Zwei Edelstahlpfosten halten die Trägerplatte sicher an Ort und Stelle und sorgen so für leises, klapperfreies Mischen. Die Trägerplatte lässt sich leicht einstellen, indem Sie die Knöpfe lösen und die Trägerplatte nach oben und unten bewegen. Die kreisförmige Nut um die Oberseite des höheren Pfostens ermöglicht es, die Trägerplatte vom Tablett wegzuschwenken, um Proben einfach zu entnehmen. Die Saugnapffüße dämpfen die Bewegung und verhindern, dass sich die Einheit auf der Werkbank bewegt. Aus Edelstahl mit korrosionsbeständiger Farbe. Ausgestattet mit einem leistungsstarken Permanentmagnetmotor mit abgedichteten Kugellagern. Der Motor ist für Dauerbetrieb ausgelegt.

Lieferant: asecos

Beschreibung: Dank innovativer Kulissentechnik bieten V-MOVE-90 Sicherheitsschränke gleiches Lagervolumen wie Standardschränke – bei halber Schrankbreite.

Artikel-Nr: (BOSSBS-1506R-A647)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1506R-A647

Beschreibung: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11804R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11804R-CY7

Beschreibung: Guanine nucleotide-exchange proteins (GEPs) accelerate replacement of bound GDP with GTP and thereby activate ADP-ribosylation factors (ARFs), a family of guanine nucleotide-binding proteins that play an important role in intracellular vesicular trafficking. GEPs comprise two major families, large GEPs that are inhibited by brefeldin A (BFA), a protein that effects golgi structure, and a group of smaller GEPs that are insenstive to BFA. Two genes for GEPs found on human chromosomes 8 and 20 encode BFA sensitive GEPs designated BIG1 and BIG2. Both GEPS contain a sec7 domain that is responsible for their brefeldin inhibition and also their catalytic activity. In vivo, BIG1 and BIG2 exist in macromolecular complexes that move between the golgi membranes and cytosol. BIG2 associates with PKA regulatory subunits, implying that BIG2 may act as an A kinase-anchoring protein (AKAP) that could coordinate the cAMP and ARF regulatory pathways.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-6455R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-6455R-CY5.5

Beschreibung: Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChR?, also known as LNCR2, PAOD2, NACHRA3 or CHRNA3, is a 505 amino acid multi-pass membrane protein that belongs to the ligand-gated ion channel receptor family and may play a role in neurotransmission.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11772R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-11772R

Beschreibung: Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-3309R-A750)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-3309R-A750

Beschreibung: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

UOM: 1 * 100 µl

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Lieferant: Avantor Fluid Handling

Beschreibung: Move fluids with viscosities up to 11,000 cp.

Artikel-Nr: (BOSSBS-13338R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-13338R-CY7

Beschreibung: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-5663R)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-5663R

Beschreibung: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-4611R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4611R-CY5.5

Beschreibung: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

UOM: 1 * 100 µl

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Artikel-Nr: (BOSSBS-1506R-CY5.5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1506R-CY5.5

Beschreibung: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-4611R-PE)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4611R-PE

Beschreibung: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

UOM: 1 * 100 µl

Sale