Sie suchten nach: Enzyme

Artikel-Nr: (PRSI92-367)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 92-367

Beschreibung: PAPSS1 is a bifunctional enzyme with both ATP sulfurylase and APS kinase activity. In the N-terminal section, it belongs to the APS kinase family; while the C-terminal section belongs to the sulfate adenylyltransferase family. PAPSS1 can be inhibited by chlorate, and is expressed in many tissues, such as high endothelial venules (HEV) cells and in cartilage. PAPSS1 mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate. In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. PAPSS1 also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.

UOM: 1 * 50 µG

Sale

Artikel-Nr: (PRSI91-762)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 91-762

Beschreibung: Protein Disulfide-Isomerase A4 (PDIA4) is an endoplasmic reticulum luminal protein that belongs to the protein disulfide isomerase family. Human PDIA4 is synthesised as a 625 amino acid precursor that contains a 20 amino acid signal sequence, and a 625 amino acid mature chain, including three thioredoxin domains. PDIA4 catalyses the rearrangement of -S-S- bonds in proteins and is thought to be a deoxycytidine kinase. In addition, PDIA4 serves as a proteases protein disulfide isomerase, phospholipase or an arrangement of these.

UOM: 1 * 50 µG

Sale

Artikel-Nr: (PRSI91-259)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 91-259

Beschreibung: Hydroxyacid Oxidase 1 (HAO1) is an enzyme that belongs to the FMN-Dependent alpha-Hydroxy Acid Dehydrogenase family. HAO1 contains 1 FMN Hydroxy Ccid Dehydrogenase domain. HAO1 is expressed primarily in the liver and pancreas. This protein has 2-Hydroxyacid Oxidase activity. Most HAO1 is active on the 2-Carbon substrate Glycolate, but it can also be active on 2-Hydroxy fatty acids, with higher activity towards 2-Hydroxy Palmitate and 2-Hydroxy Octanoate.

UOM: 1 * 50 µG

Sale

Artikel-Nr: (PRSI91-745)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 91-745

Beschreibung: Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).

UOM: 1 * 50 µG

Sale

Artikel-Nr: (PRSI92-618)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 92-618

Beschreibung: Messenger RNA (mRNA) degradation plays a key role in the control of gene expression in all organisms by limiting the number of times that each mRNA molecule can be used as a template for protein synthesis. RNA pyrophosphohydrolase, also called RppH, is a master regulator of 5'-dependent mRNA decay. It accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage. RppH preferentially hydrolyses diadenosine penta-phosphate with ATP as one of the reaction products, and can be able to hydrolyse diadenosine hexa- and tetra-phosphate. However, this protein has no activity on diadenosine tri-phosphate, ADP-ribose, NADH and UDP-glucose. In the meningitis causing strain<i> E. coli</i> K1, it has been shown to play a role in HBMEC (human brain microvascular endothelial cells) invasion <i>in vitro</i>.

UOM: 1 * 50 µG

Sale

Artikel-Nr: (PRSI91-948)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 91-948

Beschreibung: Fructose-1,6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyses the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.

UOM: 1 * 50 µG

Sale

Artikel-Nr: (PRSI90-366)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 90-366

Beschreibung: NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalysing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H₂O = AMP + diphosphate + NAD+ + L-glutamate.

UOM: 1 * 50 µG

Sale

Artikel-Nr: (PRSI90-365)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 90-365

Beschreibung: NAD kinase catalyses the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosynthetic processes such as fatty acid biosynthesis. NAD kinase from <i>Mycobacterium tuberculosis</i> is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP+ by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity: ATP + NAD+ = ADP + NADP+.

UOM: 1 * 50 µG

Sale

Artikel-Nr: (PRSI92-523)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 92-523

Beschreibung: Mouse Ca14,also known as Carbonic anhydrase 14,is a member of large family of zinc metalloenzymes .It could catalyse reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumours and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system

UOM: 1 * 50 µG

Sale

Artikel-Nr: (PRSI91-408)

Lieferant: ProSci Inc.

Hersteller Artikel Nummer : 91-408

Beschreibung: Chitinase-3-Like Protein 1 (CHI3L1) belongs to the glycosyl hydrolase 18 family. CHI3L1 is expressed in activated macrophages, articular chondrocytes, synovial cells as well as in liver. It lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. CHI3L1 is thought to play a role in defense against pathogens, or in tissue remodeling, and in the capacity of cells to respond to and cope with changes in their environment. In addition, CHI3L1 is associated with susceptibility to asthma-related traits type 7 (ASRT7) which assessed by methacholine challenge test, serum IgE levels, atopy, and atopic dermatitis.

UOM: 1 * 50 µG

Sale

Artikel-Nr: (MDTC25-054-CI)

Lieferant: Corning

Hersteller Artikel Nummer : 25-054-CI

Beschreibung: Trypsin is used to enzymatically release adherent cells from tissue culture plates for passaging

UOM: 1 * 6 ST

Zertifikate Sale

Lieferant: US Biological

Beschreibung: Cellulase (Onozuka R-10) is a multi-component enzyme system derived from <i>Trichoderma viride</i> and contains cellulase, alpha-amylase, hemicellulase, pectinase and protease activities.

Lieferant: Merck Millipore (Oncogene)

Beschreibung: Horseradish peroxidase

Zertifikate

Lieferant: Thermo Fisher Scientific

Beschreibung: Yeast lytic enzyme

Sicherheitsdatenblätter Zertifikate

Lieferant: Merck Millipore (Novagen)

Beschreibung: Biotinylated Thrombin has covalently attached biotin for easy removal of the enzyme from cleavage reactions using immobilised streptavidin. This preparation is tested for activity using the same assay as for unmodified thrombin, and for >99% binding to streptavidin agarose.

Artikel-Nr: (A4148.0100)

Lieferant: PanReac AppliChem

Hersteller Artikel Nummer : A4148.0100

Beschreibung: Pig Trypsin (from Pancreas)

UOM: 1 * 100 g

Zertifikate Sale