Sie suchten nach: Antikörper

Artikel-Nr: (BOSSBS-15573R-A750)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-15573R-A750

Beschreibung: Ig delta chain C region is an allelic product of the human IGHD gene. The two known IGHD alleles, IGHD*01 and IGHD*02, respectively produce isoforms 1, a secreted protein, and 2, a single-pass type I membrane protein. A member of the adaptive immune system, IgD are monomers expressed by activated B cells. Containing 3 Ig-like (immunoglobulin-like) domains, IgD chain C is located on chromosome 14 within the human heavy chain locus, lying on the 3? side of the IgM chain C region from the V-D-J cassette. Polyadenylation at certain sites along the heavy chain locus likely effects the mechanism that determines the alternative splicing event which results in the expression of either IgD chain C or IgM chain C. Some studies have suggested that antigenic coactivation of IgD+ B cells can have a negative influence on bone resorption during infectious events.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-7746R-CY7)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-7746R-CY7

Beschreibung: Together with dynein may be involved in spindle assembly and cytokinesis.Tissue specificity:Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-15574R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-15574R-A350

Beschreibung: IGIP.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-15533R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-15533R-A350

Beschreibung: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-9061R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-9061R-A680

Beschreibung: Teneurin-3, also known as Ten-3, TNM3 or ODZ3, is a 2,699 amino acid single-pass type II membrane protein that contains 25 YD repeats, 8 EGF-like domains, 5 NHL repeats and one teneurin N-terminal domain. Localised to the membrane and expressed in brain, testis and ovary, Teneurin-3 exists as a disulfide-liked homodimer that is thought to function as a cellular signal transducer. Additionally, Teneurin-3 may participate in eye-specific patterning in the visual pathway and is required for aligned binocular vision. The gene encoding Teneurin-3 maps to chromosome 4. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes, one of which is the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-9062R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-9062R-CY5

Beschreibung: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-9062R-FITC)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-9062R-FITC

Beschreibung: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1223R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1223R-A488

Beschreibung: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1223R-A350)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1223R-A350

Beschreibung: This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-4698R-A555)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4698R-A555

Beschreibung: May be involved in transcriptional regulation of both viral and cellular genes by interacting with the host DNA-binding protein RBPJ.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-8217R-A647)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8217R-A647

Beschreibung: FAM59B

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1173R-CY5)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1173R-CY5

Beschreibung: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-4538R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-4538R-A488

Beschreibung: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-8217R-A488)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8217R-A488

Beschreibung: FAM59B

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-1173R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-1173R-A680

Beschreibung: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity).

UOM: 1 * 100 µl

Sale

Artikel-Nr: (BOSSBS-8216R-A680)

Lieferant: Bioss

Hersteller Artikel Nummer : BS-8216R-A680

Beschreibung: Isoform 1 and isoform 3 are widely expressed with highest levels in retina and testis, with isoform 1 being the mot abundant in all tissues tested.Involvement in disease:Defects in FAM161A are the cause of retinitis pigmentosa type 28 (RP28) . A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

UOM: 1 * 100 µl

Sale