Anti-ALAS2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Lieferant: Bioss
BS-9516R-HRP
BOSSBS-9516R-HRPEA 1200 CHF
BOSSBS-9516R-HRP
Anti-ALAS2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Antikörper
5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region containsMore Product Information
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