Anti-CDK4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Lieferant: Bioss
BS-8682R-A488
BOSSBS-8682R-A488EA 1190 CHF
BOSSBS-8682R-A488
Anti-CDK4 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Antikörper
The activation of RaP1 by cAMP is independent of PKA and is mediated by recently discovered family of guanine nucleotide exchange factors (GEFs) called cAMP-GEFs or Epacs. The Epac signaling therefore represents a novel mechanism for cAMP signaling with in the cAMP cascade. There are 2 members of the Epac family, Epac1 and Epac 2. Both proteins are multidomain proteins containing an autoinhibitory cAMP-binding domain that inhibits the catalytic region and a DEP domain (dishevelled, Egl-10 and pleckstrin homology domain) targeting the membrane anchors. EPAC2 has an additional cAMP-bindingMore Product Information
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