Anti-RB1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Lieferant: Bioss
BS-2777R-HRP
BOSSBS-2777R-HRPEA 1210 CHF
BOSSBS-2777R-HRP
Anti-RB1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
Antikörper
Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, SUV42H1 and SUV42H2, leadingMore Product Information
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TECHNISCHE DATEN

Antigen-Symbol RB1
Environmentally Preferable
Antigen-Name Retinoblastoma Protein
Antigen-Synonyme RB1|pRb|OSRC|pp110|PP110|P105-RB|RB|Retinoblastoma-associated protein|p105-Rb
Antikörper-Typ Primär
Klonalität Polyklonal
Konjugation HRP (Horseradish Peroxidase)
Reaktivität Human,Rat,Mouse
Wirt Rabbit
Gen-ID 5925
Isotyp IgG
Western blot Yes
ImmunoChemie Yes
Immunogen 68-116/928
Form liquid
Reinigung Purified by Protein A
Konzentration 1 μg/μl
Kreuzadsorption No
Lagerungspuffer Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% Gentamicin. Store at 4°C for 12 months.
Lagertemperatur Store at 4°C for 12 months
Transporttemperatur 4°C

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